* Includes many descriptive figures
* Topics covered include the role of mitochondrial function, the use of ARTs to regulate mtDNA disease, nuclear transfer, and more
* Latest volume in the series that covers 10 reviews from leading authorities in developmental biology
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. These volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
Developmental biologists, cell biologists, genetics researchers, molecular biologists, and plant and animal biologists
The Mitochondrion in the Germline and Early Development, 1st Edition
Section I. The mitochondrion and gametes
The role of the mitochondrion in sperm function. Is there a place for oxidative phosphorylation or is this a purely glycolytic process?
Eduardo Ruiz-Pesini, Carmen Díez-Sánchez, Manuel José López-Pérez and José Antonio Enríquez
The role of mitochondrial function in the oocyte and embryo
Remi Dumollard, Michael Duchen, John Carroll
Mitochondrial DNA in the Oocyte and the developing embryo
Pascale May-Panloup, Marie-Françoise Chretien, Yves Malthier, Pascal Reynier
Section II. Transmission
Mitochondrial DNA and the mammalian oocyte
Eric A. Shoubridge and Timothy Wai
Mitochondrial disease - its impact, aetiology and pathology
McFarland R, Taylor RW and Turnbull DM
Cybrid models of mtDNA disease and transmission, from cells to mice
Ian A. Trounce, Carl A. Pinkert
Section III. The use of ARTs to regulate mtDNA disease.
The use of Micromanipulation Methods as a Tool to Prevention of Transmission of Mutated Mitochondrial DNA
Helena Fulka, Josef Fulka, Jr.
Difficulties and possible solutions in the Genetic Management of mtDNA disease in the pre-implantation embryo
Joanna Poulton, Pippa Oakeshott, Stephen H. Kennedy
Section IV. The effects of invasive ARTs on mtDNA transmission
Impact of assisted reproductive techniques: a mitochondrial perspective from the cytoplasmic transplantion
Carol Brenner, A. J. Harvey, T. C. Gibson
Nuclear Transfer - preservation of a nuclear genome at the expense of its associated mtDNA genome(s)
Emma J. Bowles, Keith H. S. Campbell, Justin C. St. John