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Structural Biology Using Electrons and X-rays
 
 

Structural Biology Using Electrons and X-rays, 1st Edition

An Introduction for Biologists

 
Structural Biology Using Electrons and X-rays, 1st Edition,Michael F Moody,ISBN9780123705815
 
 
 

M Moody   

Academic Press

9780123705815

9780080919454

464

235 X 191

An accessible introduction to the two major diffraction-based techniques of structural biology

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Key Features

*Emphasis on common principles underlying all diffraction-based methods

*Thorough grounding in theory requires understanding of only simple algebra

*Visual representations and explanations of challenging content

*Mathematical detail offered in short-course form to parallel the text

Description

Structural Biology Using Electrons and X-rays is the perfect book to provide advanced undergraduates or graduate students with an accessible introduction to the two major diffraction-based techniques of structural biology. While concentrating on electron cryo-microscopy with image analysis, it also includes X-ray crystallography in a coherent survey of fundamental principles. Starting with Fourier transforms and progressing through optics and imaging principles, symmetry and three-dimensional reconstruction theory, Structural Biology Using Electrons and X-rays ends in an account of the latest methods adapted to crystals, helices, viral heads, and single particles.

Readership

Graduate and advanced undergraduate students in biochemistry, molecular biology, and biological and medical physics; research biologists using electron microscopy

Michael F Moody

Structural Biology Using Electrons and X-rays, 1st Edition

Part I: Fourier Transforms

1. Overview

2. Correlations & Convolutions

3. Fourier Fundamentals

4. Digital Fourier Transforms

5. Filters

6. Two-Dimensional FTs

Part II: Optics

7. Microscopy with Rays

8. Waves

9. Wave Imaging

Part III: Further Mathematical Methods/General Aspects

10. Symmetry

11. Statistics & Matrices

12. The Third Dimension

Part IV: Image Analysis/Structure Determination

13. Special Symmetries

14. Crystalline Sheets

15. Helices

16. Icosahedral Particles

17. Unsymmetrical ("Single") Particles

18. Distortion Correction

19. FT Mathematics

20. Elementary Matrices

 
 
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