@bul:* Describes the mechanisms involved in cell death and the biochemical changes occurring during an ischaemic episode
* Presents the different factors affecting the neurodegenerative process and how compounds acting on these systems may lead to novel neuroprotective agents
* Reviews in vitro and in vivo models of stroke and the activity of putative neuroprotective drugs
* Discusses the application of preclinical data to formulate approaches to a clinical problem
* Provides detailed reviews of both completed clinical trials and those currently underway
General Description of Series
Since 1959, International Review of Neurobiology has been a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.
General Description of Volume
Stroke is the third major cause of death in the western world, and recent data provide hope that treatments may soon be available. Written by world experts on the mechanisms involved in neurodegeneration, Neuroprotective Agents and Cerebral Ischaemia presents an up-to-date review of current research and developing therapies. This book is essential reading for all clinicians and researchers searching for neuroprotective drugs.
Researchers, clinicians, and graduate students in neuroscience, cell genetics, pharmacology, biology, and physiology.
Neuroprotective Agents and Cerebral Ischaemia, 1st Edition
Mechanisms of Nerve Cell Death: Apoptosis or Necrosis after Cerebral Ischaemia, R.M.E. Chalmers-Redman, A.D. Fraser, W.Y.H. Ju, J. Wadia, N.A. Tatton, and W.G. Tatton
Changes in Ionic Fluxes during Cerebral Ischaemia, T. Kristián and B.K. Siesjö
Techniques for Examining Neuroprotective Drugs in Vivo
, A.R. Green and A.J. Cross
Techniques for Assessing Neuroprotective Drugs in Vitro
, M. P. Goldberg, U. Strasser and L.L. Dugan
Calcium Antagonists: Their Role in Neuroprotection, A.J. Hunter
Sodium and Potassium Channel Modulators: Their Role in Neuroprotection, T.P. Obrenovich
NMDA Antagonists: Their Role in Neuroprotection, D.L. Small and A.M. Buchan
Development of the NMDA Ion-Channel Blocker Aptiganel Hydrochloride as a Neuroprotective Agent for Acute CNS Injury, R.N. McBurney
Pharmacology of AMPA Antagonists and their Role in Neuroprotection, R. Gill and D. Lodge
GABA and Neuroprotection, P.D. Lyden
Adenosine and Neuroprotection, B.B. Fredholm
Interleukins and Cerebral Ischaemia, N.J. Rothwell, S.A. Loddick, and P. Stroemer
Nitrone-Based Free Radical Traps as Neuroprotective Agents in Cerebral Ischaemia and other Pathologies, K.Hensley, J.M. Carney, C.A. Stewart, T. Tabatabaie, Q. Pye, and R.A. Floyd
Neurotoxic and Neuroprotective Roles of Nitric Oxide in Cerebral Ischaemia, T. Dalkara and M.A. Moskowitz
A Review of Earlier Clinical Studies on Neuroprotective Agents and Current Approaches, N.G. Wahlgren
Contents of Recent Volumes.
Quotes and reviews
@qu:"In balance, I recommend this book as a superior volume, whose high 'power-to-weight ratio,' readability, and availability in paperback make it attractive for personal use."
@source:--TRENDS IN NEUROSCIENCES