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Immunopharmacology of Joints and Connective Tissues
 
 

Immunopharmacology of Joints and Connective Tissues, 1st Edition

 
Immunopharmacology of Joints and Connective Tissues, 1st Edition,Clive Page,M. Davies,John Dingle,ISBN9780122063459
 
 
 

Page   &   Davies   &   Dingle   

Academic Press

9780122063459

288

229 X 152

Print Book

Hardcover

In Stock

Estimated Delivery Time
USD 225.00
 
 

Description

The consequences for diseases involving the immune system such as AIDS, and chronic inflammatory diseases such as bronchial asthma, rheumatoid athritis, and atherosclerosis, now account for a considerable economic burden to governments worldwide. In response there has been an enormous research effort investigating the basic mechanisms underlying such diseases, and a tremendous drive to identify novel therapeutic applications for their preventions and treatment. Though a plethora of immunological studies have been published in recent years, little has been written about the implications of such research for drug development. As a consequence, this area has not gained the prominence of other new fields such as molecular pharmacology or neuropharmacology, and a focal information source for many pharmacologists interested in diseases of the immune system remains unpublished. The Handbook of Immunopharmacology series provides such a source through the commissioning of a comprehensive collection of volumes on all aspects immunopharmacology. Editors have been sought after for each volume who are not only active in their respective areas of expertise, but who also have distinctly pharmacological bias to their research. The series follows three main themes, each represented by volumes on individual component topics. The first covers each of the major cell types and classes of inflammatory responses that can affect them ("Systems"). The third covers different classes of diseases as well as those under development ("Drugs").

Clive Page

Affiliations and Expertise

King's College London, U.K.

View additional works by Clive Page

M. Davies

Affiliations and Expertise

Strangeways Research Laboratories, Cambridge, U.K.

John Dingle

Affiliations and Expertise

Strangeways Research Laboratories, Cambridge, U.K.

Immunopharmacology of Joints and Connective Tissues, 1st Edition

Contributors.
Series Preface.
Preface.
Introduction.
The Background to Autoimmunity, W.M. Williams, M.R. Ehrenstein, and D.A. Isenberg.
Immunological Tolerance and its Implications for Autoimmunity, N.A. Mitchison.
Peptide Blockade and Antigen-specific Modulation of Autoimmune Disease, D.C. Wraith.
Monoclonal Antibody Therapy of Experimental Arthritis - Comparison with Cyclosparin A for Elucidating Cellular and Molecular Disease Mechanisms, M.E.J. Billingham.
Anti-CD4 and Other Antibodies to Cell Surface Antigens for Therapy, F. Emmrich, H. Schulze-Koops, and G. Burmester.
Are Imbalances in Cytokine Function of Importance in the Pathogenesis of Rheumatoid Arthritis?, M. Feldmann, F.M. Brennan, E.R. Abney, A. Hales, Y. Chernajovsky, P. Katsikis, A. Corcoran, C. Haworth, A. Cope, D. Gibbons, C.Q. Chu, M. Field, B. Deleuran, R.O. Williams, and R.N. Maini.
Naturally Occuring Inhibitors of Cytokines, W.P. Arend and J.-M. Dayer.
Soluble Immunopeptides in Inflammatory Arthritis, J.A. Symons and G.W. Duff.
Inflammatory Reactions in Arthritis, H.-G. Fassbender.
Connective Tissue Destruction in Rheumatoid Arthritis: Therapeutic Potential of Selective Metalloproteinase Inhibitors, B. Henderson and S. Blake.
Lysosomal Cysteine Endopeptidases in the Degradation of Cartilage and Bone, D.J. Buttle.
Glossary.
Key to Illustrations.
Index.
 
 
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