Introduction to Psychoneuroimmunology

Introduction to Psychoneuroimmunology, 2nd Edition

Introduction to Psychoneuroimmunology, 2nd Edition,Jorge Daruna,ISBN9780123820495


Academic Press




229 X 152

Presents an overview of psychoneuroimmunology, the most integrative health science discipline, which focuses on the biological processes at all levels that operate to sustain health in the face of diverse challenges posed by changing environments. 

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Key Features

  • Single authored for consistency of breadth and depth, with no redundancy of coverage between chapters

  • Covers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others

  • Expanded use of figures, tables, and text boxes

  • Online test bank for professors


Health is maintained by the coordinated operation of all the biological systems that make up the individual. The Introduction to Psychoneuroimmunology, 2e, presents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader.


Psychologists, neuroscientists, endocrinologists, immunologists, psychiatrists, physicians and pre- and postdoctoral students in psychology, the neurosciences, microbiology and immunology, endocrinology, physiology, and pharmacology.

Jorge Daruna

Affiliations and Expertise

Ochsner Clinic Foundation, New Orleans, Louisiana, U.S.A.

Introduction to Psychoneuroimmunology, 2nd Edition

CHAPTER 1 - Introduction

CHAPTER 2 - Historical Antecedents

CHAPTER 3 - Immune System Basics

CHAPTER 4 - Endocrine-Immune Modulation

CHAPTER 5 - Neuroimmune Modulation

CHAPTER 6 - Stress, Contextual Change, and Disease

CHAPTER 7 - Psychosocial Stress: Neuroendocrine and Immune Effects

CHAPTER 8 - Infection, Allergy, and Psychosocial Stress

CHAPTER 9 - Cancer, Autoimmunity, and Psychosocial Stress

CHAPTER 10 - Immune Activity and Psychopathology

CHAPTER 11 - Immune Function Enhancement

CHAPTER 12 - Integration and Implications

Quotes and reviews

"This is a book that certainly comes with a ‘Wow’ factor. This updated version from a first edition published in 2004 presents itself as a succession of bioessays structured as units with subunits, so chapters and titled paragraphs. However the structure disappears into the background with the softness and strength in his writing and gently helps you to relax in your seat only to be taken on a journey of discovery of none other than your ‘innerspace’. It truly reads as a novel."--Immunology News, November 2012, page 46
"After a historical overview and basic introduction to the immune system and endocrine-immune and neuroimmune interactions, the text discusses the concept of stress and how it influences the neuroendocrine and immune systems; the influence of psychosocial stress on specific diseases, including infection, allergy, cancer, and autoimmunity; the link between immune activity and psychopathology, using examples of autism and schizophrenia; factors that can lead to immune enhancement and protect against disease, such as the role of suggestion, beliefs and expectations, social involvement and emotional expression, sleep, relaxation, exercise, and diet; and implications for healthcare research and practice. This edition has been updated to incorporate new scientific developments, such as research on additional signaling pathways that modulate the impact of stress, genome wide association studies, and the role of exposure to microbes and physical aspects of the environment. Chapters on infectious diseases, allergy, cancer, and autoimmune disorders have been reorganized to introduce the pathophysiology, epidemiology, and genetics of each disorder."--Reference and Research Book News, Inc.

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