Amyloid, Prions, and Other Protein Aggregates, Part C

Amyloid, Prions, and Other Protein Aggregates, Part C, 1st Edition

Amyloid, Prions, and Other Protein Aggregates, Part C, 1st Edition,Ronald Wetzel,Indu Kheterpal,ISBN9780121828189

Methods in Enzymology

Wetzel   &   Kheterpal   

Academic Press




229 X 152

Presents methods and protocols for working with amyloid proteins.

Print Book + eBook

USD 261.00
USD 435.00

Buy both together and save 40%

Print Book


In Stock

Estimated Delivery Time
USD 225.00

eBook Overview

VST (VitalSource Bookshelf) format

DRM-free included formats : PDF

USD 210.00
Add to Cart

Key Features

* Presents detailed protocols
* Includes troubleshooting tips
* Provides coverage on structural biology, computational methods, and biology


The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part B (volume 412) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies.


Biochemists, cell biologists, neuroscientists, and related fields engaged in protein research.

Ronald Wetzel

Affiliations and Expertise

University of Tennessee Medical Center, Knoxville, U.S.A.

View additional works by Ronald Wetzel
Information about this author is currently not available.

Amyloid, Prions, and Other Protein Aggregates, Part C, 1st Edition

Characterization of protein deposition in vitro.

Chapter 1: Purification of Polyglutamine Proteins
Chapter 2: Preparation of amyloid beta-protein for structural and functional studies.
Chapter 3: Kinetics and thermodynamics of amyloid assembly using an HPLC-based sedimentation assay. Chapter 4: Protein aggregation starting from the native, globular stete.
Chapter 5: Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy.
Chapter 6: Characterization of Amyloid Structures at the Molecular Level by Solid State Nuclear Magnetic Resonance Spectroscopy.
Chapter 7: Spin Labeling Analysis of Amyloids and other Protein Aggregates.
Chapter 8: Hydrogen-Deuterium Exchange Mass Spectrometry of Protein Aggregates.
Free Shipping
Shop with Confidence

Free Shipping around the world
▪ Broad range of products
▪ 30 days return policy

Contact Us