Chemokines, Chemokine Receptors and Disease, 1st Edition,Lisa Schwiebert,Dale Benos,Sidney Simon,ISBN9780121533557
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Multi-Volume: Current Topics in Membranes

Volume 55: Chemokines, Chemokine Receptors and Disease, 1st Edition

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Editor(s) : Schwiebert  &   Benos  &   Simon  

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Imprint: Academic Press

ISBN: 9780121533557

Pages: 400

Dimensions: 229 X 152

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Key Features

* Provides a comprehensive overview of the history, molecular biology, cell biology, pharmacology, physiology, and pathophysiology of chemokines and their receptors
* Each chapter discusses "future directions and unanswered questions" of chemokine biology
* Serves as a road map for future research

Description

This volume in the Current Topics in Membranes series discusses the biology of chemokines and their binding partners, chemokine receptors, in normal and disease-related states. Chemokines are small proteins that are important in normal immune responses. Recent research demonstrates a role for these proteins in a variety of diseases such as heart disease, allergy, asthma, and cancer. As a result of the discovery of this link to disease, the topic of chemokines and drugs that block their actions has become an intense are of study. This book presents the topics of chemokines, chemokine receptors, and related pathologies in an integrated manner that provides the reader with a comprehensive and up-to-date knowledge of these topics.

Readership

Basic scientists and clinicians studying biochemistry, cell biology, molecular biology, and biotechnology.

Lisa Schwiebert

Affiliations and Expertise

Associate Professor of Physiology and Biophysics and of Cell Biology, Research Scientist of The Gregory Fleming James Cystic Fibrosis Research Center, Birmingham, Alabama, U.S.A.

Dale Benos

Affiliations and Expertise

Department of Physiology and Biophysics, University of Alabama, Birmingham, USA

View additional works by Dale J. Benos

Sidney Simon

Affiliations and Expertise

Department of Neurobiology, Duke University Medical Center, Durham, NC, USA

View additional works by Sidney A. Simon

Chemokines, Chemokine Receptors and Disease, 1st Edition

Introduction: Overview and History of Chemokines and Their Receptors.
The Biology CXC Chemokines and Their Receptors.
The Molecular and Cellular Biology of CC Chemokines and Their Receptors.
The Molecular and Cellular Biology of C and CX3C Chemokines and Their Receptors.
Chemokines and Their Receptors in Hematopoietic Cell Development and Function.
Chemokines in Immune Surveillance of the Intestine.
Chemokines and Central Nervous System Physiology.
Chemokines and Chemokine Receptors in Pulmonary Disease.
Chemokines, Chemokine Receptors and Atherosclerosis.
CXC Chemokines in Cancer.
Chemokines and Chemokine Receptors in Infectious Disease.
New Therapies Targeting Chemokine Receptors: Can Changing the Way Cells Traffic be Used to Treat Human Disease?
»
Chemokines, Chemokine Receptors and Disease
 

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