Annual Reports in Medicinal Chemistry

Central Nervous System Diseases: K. Rasmussen and V.P. Rocco, Recent Progress in Serotonin (5-HT)1A Receptor Modulators. A.B. Reitz, M.C. Jetter, K.D. Wild, and R.B. Raffa, Centrally Acting Analgesics. E.B. De Souza, T.W. Lovenberg, D.T. Chalmers, D.E. Grigoriadis, C.W. Liaw, D.P. Behan, and J.R. McCarthy, Heterogeneity of Corticotropin Releasing Factor Receptors: Multiple Targets for the Treatment of CNS and Inflammatory Disorders. K. Shiosakiand P. Puttfarcken, Emerging Opportunities in Neuroinflammatory Mechanisms of Neurodegeneration. I.A. McDonald, N. Cosford, and J.-M. Vernier, Nicotinic Acetylcholine Receptors: Molecular Biology, Chemistry and Pharmacology. J. Gilmore, C. Dell, D. Bowman, and D. Lodge, Neuronal Calcium Channels. Cardiovascular and Pulmonary Diseases: L.A. Denner and R.A.F. Dixon, Vascular Proliferative Disease. R.M. Scarborough, Anticoagulant Strategies Targeting Thrombin and Factor Xa. J.R. Empfield and K. Russell, Potassium Channel Openers. T.F. Walsh, Progress in the Development of Endothelin Receptor Antagonists. Cancer and Infectious Diseases: J.P. Dirlam, B.H. Jaynes, and M.R. Jefson, Antibacterial Agents. J.F. Barrett and R.E. Isaacson, Bacterial Virulence as a Potential Target for Therapeutic Intervention. A.M. Nadzan, Retinoids for the Treatment of Oncological Diseases. R.C. Goldman, Biological Response Modification by beta-D-Glucans. R.E. Boehme, A.D. Borthwick, and P.G. Wyatt, Antiviral Agents. L.L. Klein and S.K. Tanaka, Therapy of Helicobacter pylori Infections: Current Status and Future Directions. Immunology, Endocrinology and Metabolic Diseases: R.L. Dowand D.K. Kreutter, Recent Advancements in the Discovery and Development of Agents for the Treatment of Diabetes. M.T. Goulet, Gonadotropin Releasing Hormone Antagonists. D.B. Reitz and K. Seibert, Selective Cyclooxygenase Inhibitors. T.H. Claus and J.D. Bloom, beta<->3-Selective Adrenergic Receptor Agonists. Z.A. Nagy and D. Vidovic [accent], The T Cell--Antigen Presenting Cell Interaction as a Site for Immunosuppressive Interventions. K. Cooper and K. Neote, Chemokinesas Therapeutic Targets. Topics in Biology: L.E. Post, Gene Therapy: Progress, New Directions, and Issues. M.C. Botfield and J. Green, SH2 and SH3 Domains: Choreographers of Multiple Signaling Pathways. B. Beutler, Programmed CellDeath Mediated by Members of the TNF Receptor Family. M.L. Gishizky, Tyrosine Kinase Induced Mitogenesis: Breaking the Link with Cancer. Topics in Drug Design and Discovery: T.S. Scanlan, Catalytic Antibodies. R.S. McDowell and D.R. Artis, Structure-Based Design from Flexible Ligands. D.J. Matthews, Applications of Biosensor Technology in Drug Discovery. N. Usman and J.A. McSwiggen, Catalytic RNA (Ribozymes) as Drugs. Trends and Perspectives: X.-M. Cheng, ToMarket, To Market--1994. D. Stirling, Potential Use of Thalidomide in HIV/AIDS. C.R. Ganellin, L.A. Mitscher, and J.G. Topliss, Educating Medicinal Chemists. W.L. Thompson, Research Investments in a Managed Care, Cost-Containment, Oligopsony. Compound Name, Code Number, and Subject Index, Volume 30. Cumulative Chapter Titles Keyword Index, Volumes 1-30. Cumulative NCE Introduction Index, 1983-1994. Cumulative NCE Introduction Index, 1983-1994, By Indication.