Volume 68: Insect Viruses, 1st Edition

Description

Baculoviruses are perhaps unique among viruses in the breadth of their biotechnological applications: these insect specific viruses are used not only for insect pest management purposes, but also as laboratory research tools for production of recombinant proteins and for protein display, and as potential vectors for human gene therapy. In addition to highlighting recent advances, this volume provides a comprehensive review of the biotechnological applications of these and other insect viruses in both the academic and private sectors.

Readership

Researchers and postgraduates within academia and industry working in virology, entomology, biotechnology, insect pest management and biological control, human gene therapy, vaccinology, plant pathology, drug discovery, and genetics

Insect Viruses, 1st Edition

Insect Viruses as Laboratory Research Tools
Milestones Leading to the Genetic Engineering of Baculoviruses as Expression Vector Systems and Viral Pesticides
Polydnavirus genes that enhance the baculovirus expression vector system
Baculovirus Display: A Multi-Functional Technology for Gene Delivery and Eukaryotic Library Development
Stably transformed insect cell lines: Tools for expression of secreted and membrane-anchored proteins and high throughput screening platforms for drug and insecticide discovery
Applications to Human and Animal Health
Protein N-glycosylation in the baculovirus-insect cell expression system and efforts to engineer insect cells to produce “mammalianized” recombinant glycoproteins
Vaccines for viral and parasitic diseases produced with baculovirus vectors
Baculoviruses and Mammalian Cell-Based Assays for Drug Screening
Baculovirus Vectors for Gene Therapy
Insect Pest Management
Genetically Modified Baculoviruses: A Historical Overview and Future Outlook
Densoviruses for Control and Genetic Manipulation of Mosquitoes
Potential Uses of Cys-Motif and Other Polydnavirus Genes in Biotechnology
Virus-derived genes for insect resistant transgenic plants
Small RNA Viruses of Insects: Expression in Plants and RNA Silencing.