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Calcium Regulation of Cellular Function
 
 

Calcium Regulation of Cellular Function, 1st Edition

 
Calcium Regulation of Cellular Function, 1st Edition,Paul Greengard,Angus Nairn,Shirish Shenolikar,Anthony Means,ISBN9780120361304
 
 
 

Greengard   &   Nairn   &   Shenolikar   &   Means   

Academic Press

9780120361304

9780080552736

416

229 X 152

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Description

Volume 30 examines the prominent role of calcium as an intracellular second messenger. Leading investigators review a wide variety of studies on how calcium enters and moves through cells, how it interacts with its many binding proteins, and how calcium and its intracellular receptor, calmodulin, control vital cellular processes. Coverage includes a detailed analysis of the mechanisms by which calcium bound to calmodulin regulates contractile proteins in smooth muscle cells. Close attention is given to the roles of calcium and calmodulin-dependent protein kinases and phosphatases in synaptic signal transduction, protein synthesis, gene expression, programmed cell death, activation of T-lymphocytes, and control of cell division cycles. Other chapters discuss studies using genetically manipulable nonmammalian organisms to further proble the functions of calcium and calmodulin.

Paul Greengard

Affiliations and Expertise

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University

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Angus Nairn

Angus C. Nairn is currently Associate Professor at The Rockefeller University. He has published a large number of papers concerned with the structure and regulation of protein kinases and phosphatases involved in signal transduction, particularly with respect to signalling by calcium.

Affiliations and Expertise

Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, U.S.A.

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Shirish Shenolikar

Affiliations and Expertise

Durham, North Carolina, U.S.A.

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Anthony Means

Affiliations and Expertise

Duke University, Durham, North Carolina, U.S.A.

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