»
Drug-Drug Interactions: Scientific and Regulatory Perspectives
 
 

Drug-Drug Interactions: Scientific and Regulatory Perspectives, 1st Edition

 
Drug-Drug Interactions: Scientific and Regulatory Perspectives, 1st Edition,J. August,Ferid Murad,M. Anders,Joseph Coyle,Albert Li,ISBN9780120329441
 
 
 

Advances in Pharmacology

August   &   Murad   &   Anders   &   Coyle   &   Li   

Academic Press

9780120329441

9780080581354

304

229 X 152

Print Book + eBook

USD 318.00
USD 530.00

Buy both together and save 40%

Print Book

Hardcover

In Stock

Estimated Delivery Time
USD 270.00

eBook
eBook Overview

VST format:

DRM Free included formats: PDF

USD 260.00
Add to Cart
 
 

Key Features

@introbul:Key Features
@bul:* Provides useful references on the science of drug-drug interactions
* Describes in a basic and comprehensive manner drug-drug interactions from the mechanistic viewpoint
* Contains original data from academic and industrial laboratories
* Presents an overview of regulatory agency positions

Description

Drug–Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug–drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug–drug interactions, the prediction of drug–drug interaction potential of new drugs, and the avoidance of clinically significant drug–drug interaction in patients.

Readership

Professionals in the pharmaceutical industry, health care industry, and governmental regulatory agencies. Students and researchers in the areas of pharmacology, toxicology, pharmacokinetics, and medicine.

J. August

Affiliations and Expertise

John Hopkins University; Department of Pharmacology, Baltimore, Maryland, U.S.A.

View additional works by J. Thomas August

Ferid Murad

Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children.

Affiliations and Expertise

University of Texas Medical School, Houston, U.S.A.

View additional works by Ferid Murad

M. Anders

Affiliations and Expertise

University of Rochester; Department of Pharmacology, New York, U.S.A.

View additional works by M. W. Anders

Joseph Coyle

Affiliations and Expertise

McLean Hospital, Harvard Medical School, Belmont, Massachusetts, U.S.A.

View additional works by Joseph T. Coyle

Albert Li

Affiliations and Expertise

In Vitro Technologies, Inc., and University of Maryland Technology Center, Baltimore, Maryland, U.S.A.

Drug-Drug Interactions: Scientific and Regulatory Perspectives, 1st Edition

J. Collins, Foreword.
A.P. Li, Preface.
A.P. Li, Overview: Scientific Basis of Pharmacokinetic Drug-Drug Interactions.
F.P. Guengerich, Role of Cytochrome P450 Enzymes in Drug-Drug Interactions.
J.M. Sauer, E.R. Stine, L. Gunawardhana, D.A. Hill, and I.G. Sipes, The Liver as a Target for Chemical-Chemical Interactions.
A.D. Rodrigues and S.L. Wong, Applications of Human Liver Microsomes in Metabolism-Based Drug-Drug Interactions.
A.P. Li, Applications of Human Hepatocytes as an Experimental System for the Evaluation of Pharmacokinetic Drug-Drug Interactions.
J.L. Ferrero and K. Brendal, Liver Slices as a Model in Drug Metabolism and Drug-Drug Interactions.
C.L. Crespi and B.W. Penman, The Use of cDNA Expressed Human Cytochrome P450 Enzymes to Study Potential Drug-Drug Interactions.
G.L. Kedderis, Pharmacokinetics of Drug Interactions.
T.N. Thompson, Experimental Models for Evaluating Enzyme Induction Potential of New Drug Candidates in Animals and Man and a Strategy for Their Use.
J.D. Balian, Metabolic Drug-Drug Interactions: Perspective from U.S. FDA Medical and Clinical Pharmacology Reviewers.
M. Jurima-Romet, Drug Interactions: Perspectives of the Canadian Directorate.

Quotes and reviews

@from:Praise for the Series
@qu:"Recommended not only to pharmacologists but also to all those in related disciplines."
@source:--NATURE
@qu:"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."
@source:--H.E. Kaufmann in CHEMOTHERAPY
@qu:"Superb reading material."
@source:--JOURNAL OF PHARMACEUTICAL SCIENCES
@qu:"This book represents a comprehensive review of drug-drug interaction and is unique since the contributors are from all facets of the workplace, including academic institutes, government, and industry... The most attractive feature of the book is its well-focused subject area with the emphasis on the importance of P-450 enzymes in drug interactions and how government regulatory agencies evaluate them... It is unique since it presents the regulatory aspects of drug evaluations as an integral part of the science of drug-drug interactions."
@source:--Rajendar Mehta, PhD, University of Illinois at Chicago College of Medicine for DOODY'S PUBLISHING
 
 
Back To School Sale | Use Promo Code BTS14
Shop with Confidence

Free Shipping around the world
▪ Broad range of products
▪ 30 days return policy
FAQ