Presents a different view of medicinal chemistry through personal accounts by eminent scientists describing their lifetime experiences in the field. Also illustrates 14 case studies of successful drug discovery and development.
Readership
For students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.
Comprehensive Medicinal Chemistry II, 1st Edition
Volume 8 Case Histories and Cumulative Subject Index
Personal Essays
8.01 Introduction
8.02 Reflections on Medicinal Chemistry Since the 1950s
8.03 Medicinal Chemistry as a Scientific Discipline in Industry and Academia: Some Personal Reflections
8.04 Some Aspects of Medicinal Chemistry at the Schering-Plough Research Institute
Case Histories
8.05 Viread
8.06 Hepsera
8.07 Ezetimibe
8.08 Tamoxifen
8.09 Raloxifene
8.10 Duloxetine
8.11 Carvedilol
8.12 Modafinil, A Unique Wake-Promoting Drug: A Serendipitous Discovery in Search of a Mechanism of Action
8.13 Zyvox
8.14 Copaxone
8.15 Ritonavir and Lopinavir/Ritonavir
8.16 Fosamax
8.17 Omeprazole
8.18 Calcium Channel a2–d Ligands: Gabapentin and Pregabalin
Cumulative Subject Index
