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Vitamins and Hormones
1st Edition, Volume 70 - March 3, 2005
Editor: Gerald Litwack
Language: English
eBook ISBN:9780080458045
9 7 8 - 0 - 0 8 - 0 4 5 8 0 4 - 5
First published in 1943, VITAMINS AND HORMONES is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones…Read more
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First published in 1943, VITAMINS AND HORMONES is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, VITAMINS AND HORMONES continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.
* First published in 1943, Vitamins and Hormones is AP's longest running serial * Each volume contains cutting edge reviews by leading contributors
Researchers, professors, and graduate students studying the molecular and cellular biology of vitamins, hormones, and related factors and co-factors
Former Editors
Publisher Summary
Contributors
Publisher Summary
Preface
Publisher Summary
1: Extrapituitary Effects of the Growth Hormone-Releasing Hormone
Abstract
I Introduction
II Endocrine Role of GHRH in Carcinogenesis
III Various Cancers and Normal Tissues That Produce and Respond to GHRH
IV Direct Effects of GHRH in Carcinogenesis
V Mechanism of Action for Locally Produced GHRH
VI Conclusions and Perspectives
Acknowledgements
2: IRS-1 and Vascular Complications in Diabetes Mellitus
Abstract
I Introduction
II Insulin Receptor Superfamily
III Insulin Receptor Substrates
IV Signaling Pathways Regulated by IRS-1
V IRS-1 and Insulin Resistance
VI The Role of IRS-1 in Atherothrombotic Complications
VII Summary and Future Perspectives
Acknowledgements
Appendix List of Abbreviations
3: Structural and Functional Properties of CCN Proteins
Abstract
I Discovery of the CCN Gene Family
II CCN Family Modular Structure
III CCN Family and Heparin Interactions
IV CCN Gene Family and Integrins
V CCN2 Binding to LRP
VI CCN Gene Family and Intracellular Signaling
VII The Link Between TGF-β and CCN2
VIII CCN Gene Family Action in Normal Biological Processes
IX CCN Protein Action in Pathological Disease Processes
X Summary
Acknowledgements
4: Stanniocalcin: No Longer Just a Fish Tale
Abstract
I General Introduction
II Early Studies on the Discovery and Function of Stanniocalcin in Fish
III The Discovery of Mammalian Stanniocalcin
IV The Sequestering Hypothesis
V Future Directions
Acknowledgements
5: Thyroid Hormone Transporters
Abstract
I Introduction
II Thyroid Hormone Transporters
III Conclusions
6: Phytoestrogens and Colorectal Cancer Prevention
Abstract
I Introduction
II Phytoestrogens
III Experimental Studies
IV Concluding Remarks
Acknowledgements
7: Transcriptional Activities of Retinoic Acid Receptors
Abstract
I Introduction
II Retinoid Physiology
III Retinoid-Binding Proteins
IV Transcriptional Regulation by Retinoic Acid Receptors: The Transactivation Process
V Transcriptional Regulation by Retinoic Acid Receptors: The Transrepression Process
VI Nongenomic Effects of Retinoids
VII Conclusion
8: Biochemical and Ionic Signaling Mechanisms for ACTH-Stimulated Cortisol Production
Abstract
I Introduction
II ACTH Receptors: cAMP- and Ca2+-Dependent Signaling
III Ionic Mechanisms in ACTH-Stimulated Cortisol Secretion
IV Chronic Control of Ion Channel Expression by ACTH in AZF Cells
V Summary and Prospects
9: ATP-Dependent Chromatin Remodeling Complexes and Their Role in Nuclear Receptor-Dependent Transcription In Vivo
Abstract
I Introduction
II ATP-Dependent Chromatin Remodeling Complexes
III ATP-Dependent Chromatin Remodeling Complexes and Their Role in Nuclear Receptor-Mediated Transcription
IV Conclusions
10: Novel Roles for Acylation Stimulating Protein/C3adesArg: A Review of Recent In Vitro and In Vivo Evidence
Abstract
I Introduction
II ASP Production
III ASP Function and Role in Metabolism
IV ASP Effects on Insulin, Cytokine, and Pituitary Hormone Secretion
V Discussion
Acknowledgements
Appendix Abbreviations
11: STAT3 and Transactivation of Steroid Hormone Receptors
Publisher Summary
I Introduction
II STAT Structure
III Mechanisms of STAT Activation and Regulation
IV The JAK/STAT Pathway In Nonmammalian Systems
V STATs in Human Malignancy
VI STAT3 and Steroid Hormone Receptor Activation
VII Conclusion
12: Coactivators in Gene Regulation by STAT5
Abstract
I Signal Transduction by STAT5
II Physiological Role of STAT5
III Structure and DNA-Binding of STAT5
IV Transcriptional Activation by STAT5
V Interaction of STAT5 with Other Signaling Pathways
VI Regulation of STAT5 Transcriptional Activity by Secondary Modifications
VII Conclusions
13: New Insights into the Regulation of Mammalian Sex Determination and Male Sex Differentiation
Abstract
I Introduction
II The Genetics of Male Sex Determination
III Hormonal Regulation of Male Sex Differentiation
IV Conclusion
14: The Role of Alcohol and Steroid Hormones in Human Aggression
Abstract
I Introduction
II Alcohol
III The Endocrinology of Aggression
IV The Effect of Alcohol on Steroid Hormones
V Conclusions
Index
Publisher Summary
No. of pages: 451
Language: English
Edition: 1
Volume: 70
Published: March 3, 2005
Imprint: Academic Press
eBook ISBN: 9780080458045
GL
Gerald Litwack
Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)
Affiliations and expertise
Emeritus Founding Chair and Professor, Geisinger Commonwealth School of Medicine, United States
Emeritus Professor, Rutgers University, United States