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Current Topics in Developmental Biology
1st Edition, Volume 67 - May 13, 2005
Editor: Gerald P. Schatten
Language: English
Hardback ISBN:9780121531676
9 7 8 - 0 - 1 2 - 1 5 3 1 6 7 - 6
eBook ISBN:9780080458328
9 7 8 - 0 - 0 8 - 0 4 5 8 3 2 - 8
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal…Read more
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Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
Volume 67, covers innovative topics such as Control of Food-intake through Regulation of camp, regeneration of deer antlers, factors affecting male song evolution in drosophila montana, skeletal stem cells in regenerative medicine, and so much more.
Contains 10 vital contributions from leading minds in developmental biology
Presents an analysis of contemporary topics such as regeneration of stem cells, drosophila montana, and programmed cell death in plants
Offers 17 full color figures in detail of the chapters
Developmental biologists, cell biologists, genetics researchers, and molecular biologists
1: Deer Antlers as a Model of Mammalian Regeneration
I Introduction
II Regulation of the Antler Development and Regeneration
Acknowledgments
2: The Molecular and Genetic Control of Leaf Senescence and Longevity in Arabidopsis
I Introduction
II Arabidopsis as a Model Plant for Studying Leaf Senescence
III Senescence Symptoms
IV Identification of Senescence-Associated Genes and Their Functional Analysis
V Regulatory Mode of Senescence-Associated Genes
VI Regulatory Factors: Molecular Genetic Regulation of Leaf Senescence
VII Biotechnological Application of Senescence
VIII Conclusions and Future Challenges
Acknowledgments
3: Cripto-1: An Oncofetal Gene with Many Faces
I Introduction
II Structure and Genomic Organization of the EGF-CFC Gene Family
III Function and Expression of EGF-CFC Genes During Embryonic Development
IV EGF-CFC Proteins in Mammary Gland Development
V EGF-CFC Proteins in Transformation and Tumorigenesis
VI Intracellular Signaling Pathways Activated by Cripto-1
VII Expression of Cripto-1 in Human Carcinomas and Premalignant Lesions
VIII Cripto-1 as Target for Therapy in Human Cancer
IX Conclusions and Perspectives
Acknowledgments
4: Programmed Cell Death in Plant Embryogenesis
I Introduction
II Model Embryonic Systems
III Mechanics of Cell Death
IV Molecular Executioners
V Concluding Remarks
Acknowledgments
5: Physiological Roles of Aquaporins in the Choroid Plexus
I Aquaporin Water Channels
II Development of the Choroid Plexus
III Ion Channels in the Choroid Plexus
IV Function of AQP1 as a Gated Cation Channel
V Physiological Relevance of AQP1 Ion Channels in Choroid Plexus
VI Regulation of Cerebrospinal Fluid Production
VII Choroid Plexus “Dark Cells”
VIII Barrier Function of the Choroid Plexus
IX Neuroendocrine Function
X Pathophysiology of the Choroid Plexus
XI Conclusions
6: Control of Food Intake Through Regulation of cAMP
I Introduction
II Regulation of Feeding at the Hypothalamus
III Hypothalamic Effects of cAMP on Food Intake
IV cAMP as an Orexigenic Second Messenger
V The Anorectic Effects of cAMP in the PVN
VI Regulation of Food Intake by Leptin Requires a PI3K-PDE3B-cAMP Signaling Pathway
VII What Elevates the Intracellular cAMP Levels in the NPY-Neurons in a Negative Energy Balance State?
VIII A Working Model for Hypothalamic Control of Food Intake Involving Regulation of cAMP—A Perspective from the NPY/AgrP Neurons
IX Dysregulation of cAMP in the Hypothalamus—Implication in Obesity
7: Factors Affecting Male Song Evolution in Drosophila montana
I Background
II Male Song Variation in D. montana and Other Species of the virilis Group
III Female Preferences for Male Song Characters
IV Song as a Species-Recognition Signal
V Summary
Acknowledgments
8: Prostanoids and Phosphodiesterase Inhibitors in Experimental Pulmonary Hypertension
I Introduction
II Animal and Organ Models of Pulmonary Hypertension
III Prostanoids and PDE Inhibitors in Acute and Chronic Hypoxia
IV Prostanoids and PDE Inhibitors in Monocrotaline-Induced Pulmonary Hypertension
V Prostanoids and PDE Inhibitors in U46619-Induced Acute Pulmonary Hypertension
VI Less Frequently Used Models of Experimental Pulmonary Hypertension
VII Combination of PDE Inhibitors with Vasodilators
VIII Summary and Concluding Remarks
Acknowledgments
9: 14-3-3 Protein Signaling in Development and Growth Factor Responses
I Introduction
II 14-3-3: A Dimer with Phosphoserine-Binding Activity
III 14-3-3 Pathways in Drosophila Development
IV Interaction with the Ras-Raf Signaling Pathway
V 14-3-3 and Growth Factor Signaling
VI Phosphorylation of 14-3-3 by Sphingosine-Dependent Kinase
VII Conclusions
10: Skeletal Stem Cells in Regenerative Medicine
I Introduction
II Isolation and Characterization of MSCs from Bone Marrow
III Niche Microenvironment of BMSSCs
IV Therapeutic Uses of BMSSCs
V Delivery of BMSSCs
VI Alternative Sources of MSCs
VII Future Direction
Index
Contents of Previous Volumes
No. of pages: 368
Language: English
Edition: 1
Volume: 67
Published: May 13, 2005
Imprint: Academic Press
Hardback ISBN: 9780121531676
eBook ISBN: 9780080458328
GS
Gerald P. Schatten
Affiliations and expertise
University of Pittsburgh School of Medicine, PA, U.S.A.
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