Methods in Enzymology

The critically acclaimed laboratory standard for almost 50 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 500 volumes the series contains much material still relevant today and is truly an essential publication for researchers in all fields of life sciences, including microbiology, biochemistry, cancer research and genetics-just to name a few. Five of the 2013 Nobel Laureates have edited or contributed to volumes of MIE.

About the Editors: John N. Abelson, California Institute of Technology, Division of Biology, Pasadena, USA; Melvin I. Simon, California Institute of Technology, Division of Biology, Pasadena, USA; and Anna Marie Pyle, Howard Hughes Medical Institute, Yale University, USA.

Impact Factor 2013: 2.194 (Copyright ISI Journal Citation Report)

To view individual chapters for Methods in Enzymology, please visit Science Direct.

Praise for the Series: "Should be on the shelves of all libraries in the world as a whole collection." - CHEMISTRY IN INDUSTRY "The work most often consulted in the lab." - ENZYMOLOGIA “The Methods in Enzymology series represents the gold-standard." - NEUROSCIENCE

Book

Hydrogen Sulfide in Redox Biology Part A

Editors: Enrique Cadenas & Lester Packer Release Date: 01 Mar 2015
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Hydrogen Sulfide in Redox Biology Part B

Editors: Enrique Cadenas & Lester Packer Release Date: 15 Mar 2015
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Circadian Rhythms and Biological Clocks Part A

Editor: Amita Sehgal Release Date: 27 Jan 2015
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Riboswitches as Targets and Tools

Editor: Donald H. Burke-Aguero Release Date: 12 Jan 2015
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Mitochondrial Function

Editors: Anne Murphy & David Chan Release Date: 13 Nov 2014
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Riboswitch Discovery, Structure and Function

Editor: Donald H. Burke-Aguero Release Date: 26 Nov 2014
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The Use of CRISPR/cas9, ZFNs, TALENs in Generatin...

Editors: Jennifer A. Doudna & Erik J. Sontheimer Release Date: 13 Nov 2014
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Protein Kinase Inhibitors in Research and Medicine

Editor: Kevan Shokat Release Date: 13 Nov 2014
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Cell-wide Metabolic Alterations Associated With M...

Editors: Lorenzo Galluzzi & Guido Kroemer Release Date: 16 Jun 2014
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Methods of Adipose Tissue Biology Part A

Editor: Ormond Macdougald Release Date: 07 Feb 2014
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Conceptual Background and Bioenergetic/Mitochondr...

Editors: Lorenzo Galluzzi & Guido Kroemer Release Date: 27 May 2014
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Regulated Cell Death Part A , Apoptotic Mechanisms

Editors: Avi Ashkenazi & Junying Yuan & Jim Wells Release Date: 24 Jun 2014
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Reconstituting the Cytoskeleton

Editor: Ron Vale Release Date: 27 Mar 2014
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Endosome Signalling Part A

Editor: P. Michael Conn Release Date: 13 Jan 2014
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Endosome Signalling Part B

Editor: P. Michael Conn Release Date: 14 Jan 2014
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Research Methods in BIomineralization Science

Editor: Jim De Yoreo Release Date: 15 Nov 2013
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Laboratory Methods in Enzymology: DNA

Editor: Jon Lorsch Release Date: 23 Sep 2013
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Hydrogen Peroxide and Cell Signaling, Part B

Editors: Lester Packer & Enrique Cadenas Release Date: 15 Jul 2013
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Hydrogen Peroxide and Cell Signaling, Part A

Editors: Lester Packer & Enrique Cadenas Release Date: 08 Jul 2013
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Hydrogen Peroxide and Cell Signaling, Part C

Editors: Enrique Cadenas & Lester Packer Release Date: 29 Jul 2013
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Microbial Metagenomics, Metatranscriptomics, and ...

Editor: Ed DeLong Release Date: 08 Oct 2013
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Laboratory Methods in Enzymology: Protein Part A

Editor: Jon Lorsch Release Date: 31 Jan 2014
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Methods in Protein Design

Editor: Amy Keating Release Date: 12 Mar 2013
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Laboratory Methods in Enzymology: Cell, Lipid and...

Editor: Jon Lorsch Release Date: 12 Nov 2013
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G Protein Coupled Receptors, Modeling, Activation...

Editor: P. Michael Conn Release Date: 22 Feb 2013
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Laboratory Methods in Enzymology: RNA

Author: Jon Lorsch Release Date: 24 Sep 2013
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Cilia, Part B

Editor: Wallace F. Marshall Release Date: 16 Apr 2013
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The Unfolded Protein Response and Cellular Stress...

Editor: P. Michael Conn Release Date: 25 Feb 2011
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Protein Engineering for Therapeutics, Part A

Editors: K. Dane Wittrup & Gregory L. Verdine Release Date: 11 Jan 2012
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Natural Product Biosynthesis by Microorganisms an...

Editor: David Hopwood Release Date: 01 Nov 2012
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Nanomedicine, Infectious Diseases, Immunotherapy,...

Editor: Nejat Duzgunes Release Date: 23 May 2012
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Serpin Structure and Evolution

Editors: James Whisstock & Phillip Bird Release Date: 16 Nov 2011
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IMAGING AND SPECTROSCOPIC ANALYSIS OF LIVING CELL...

Editor: P. Michael Conn Release Date: 01 Feb 2012
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Natural Product Biosynthesis by Microorganisms an...

Editor: David Hopwood Release Date: 01 Oct 2012
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Synthetic Biology, Part A, Methods for Part/Devic...

Editor: Chris Voigt Release Date: 23 May 2011
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Nanomedicine, Cancer, Diabetes, and Cardiovascula...

Editor: Nejat Duzgunes Release Date: 30 Mar 2012
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Fluorescence Fluctuation Spectroscopy (FFS) Part B

Editor: Sergey Tetin Release Date: 18 Jan 2013
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Nucleosomes, Histones & Chromatin Part A

Editors: Carl Wu & C. Allis Release Date: 31 Aug 2012
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Biology of Serpins

Editors: James Whisstock & Phillip Bird Release Date: 18 Jul 2011
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Biothermodynamics, Part D

Editors: Michael Johnson & Jo Holt & Gary Ackers Release Date: 25 Feb 2011
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RNA helicases

Editor: Eckhard Jankowsky Release Date: 22 Jun 2012
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Natural Product Biosynthesis by Microorganisms an...

Editor: David Hopwood Release Date: 17 Oct 2012
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Synthetic Biology, Part B, Computer Aided Design ...

Editor: Chris Voigt Release Date: 09 Jun 2011
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Methods in Systems Biology

Editors: Hans Westerhoff & Malkhey Verma & Daniel Jameson Release Date: 26 Sep 2011
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The Unfolded Protein Response and Cellular Stress...

Editor: P. Michael Conn Release Date: 08 Feb 2011
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The Unfolded Protein Response and Cellular Stress...

Editor: P. Michael Conn Release Date: 08 Feb 2011
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Nucleosomes, Histones & Chromatin Part B

Editors: Carl Wu & C. Allis Release Date: 10 Sep 2012
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Gene Transfer Vectors for Clinical Application

Editor: Theodore C. Friedman Release Date: 06 Mar 2012
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Fragment Based Drug Design, Tools, Practical Appr...

Editor: Lawrence Kuo Release Date: 09 Mar 2011
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IMAGING AND SPECTROSCOPIC ANALYSIS OF LIVING CELL...

Editor: P. Michael Conn Release Date: 24 Jan 2012
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Fluorescence Fluctuation Spectroscopy (FFS), Part...

Editor: Sergey Tetin Release Date: 15 Jan 2013
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Cellulases

Editor: Harry Gilbert Release Date: 29 May 2012
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IMAGING AND SPECTROSCOPIC ANALYSIS OF LIVING CELL...

Editor: P. Michael Conn Release Date: 24 Feb 2012
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Research on Nitrification and Related Processes, ...

Editors: Martin Klotz & Lisa Stein Release Date: 04 May 2011
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Protein Engineering for Therapeutics, Part B

Editors: K. Dane Wittrup & Gregory L. Verdine Release Date: 19 Jan 2012
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Biothermodynamics, Part C

Editor: Melvin Simon Release Date: 12 Jan 2011
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Glycomics

Editor: Minoru Fukuda Release Date: 15 Sep 2010
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Research on Nitrification and Related Processes, ...

Editor: Martin Klotz Release Date: 10 Jan 2011
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Mitochondrial Function, Part B, Mitochondrial Pro...

Editors: William Allison & Anne Murphy Release Date: 15 May 2009
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Constitutive activity in receptors and other Prot...

Editor: Melvin Simon Release Date: 11 Nov 2010
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Angiogenesis: In Vitro Systems

Editor: David Cheresh Release Date: 02 Sep 2008
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Autophagy: Lower Eukaryotes and Non-Mammalian Sy...

Editor: Daniel Klionsky Release Date: 12 Dec 2008
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Angiogenesis: In Vivo Systems, Part B

Editor: David Cheresh Release Date: 29 Oct 2008
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Small GTPases in Disease, Part A

Editors: W. Balch & Channing Der & Alan Hall Release Date: 25 Apr 2008
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Translation Initiation: Cell Biology, High-throug...

Editor: Jon Lorsch Release Date: 12 Oct 2007
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Small GTPases in Disease, Part B

Editors: W. Balch & Channing Der & Alan Hall Release Date: 01 Apr 2008
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Translation Initiation: Extract Systems and Mole...

Editor: Jon Lorsch Release Date: 15 Oct 2007
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Computer Methods, Part C

Editor: Melvin Simon Release Date: 12 Jan 2011
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Nitric Oxide, Part G

Editors: Enrique Cadenas & Lester Packer Release Date: 26 Jun 2008
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RNA Turnover in Bacteria, Archaea and Organelles

Editors: Lynne E. Maquat & Cecilia Arraiano Release Date: 19 Dec 2008
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Globins and Other Nitric Oxide-Reactive Proteins,...

Editor: Robert K. Poole Release Date: 05 Feb 2008
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Mitochondrial Function, Part A, Mitochondrial Ele...

Editors: William Allison & Immo Scheffler Release Date: 20 Apr 2009
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Nitric Oxide, Part F

Editors: Enrique Cadenas & Lester Packer Release Date: 25 Apr 2008
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Glycobiology

Editor: Minoru Fukuda Release Date: 15 Sep 2010
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Two-Component Signaling Systems, Part C

Editors: Melvin Simon & Brian Crane & Alexandrine Crane Release Date: 11 Mar 2010
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Computer Methods Part B

Editors: Michael Johnson & Ludwig Brand Release Date: 19 Nov 2009
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Biothermodynamics Part A

Editors: Michael Johnson & Jo Holt & Gary Ackers Release Date: 24 Mar 2009
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Functional Glycomics

Editor: Minoru Fukuda Release Date: 15 Sep 2010
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Cryo-EM, Part C, Analyses, Interpretation, and Ca...

Editor: Grant Jensen Release Date: 14 Oct 2010
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Non-Natural Amino Acids

Editors: Tom W. Muir & John Abelson Release Date: 14 Aug 2009
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Guide to Protein Purification, 2nd Edition

Editors: Richard Burgess & Murray Deutscher Release Date: 17 Nov 2009
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Two-Component Signaling Systems, Part B

Editors: Melvin Simon & Brian Crane & Alexandrine Crane Release Date: 03 Jul 2007
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Advanced Bacterial Genetics: Use of Transposons a...

Editor: Kelly Hughes Release Date: 27 Feb 2007
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Lipidomics and Bioactive Lipids: Specialized Ana...

Editor: H. Alex Brown Release Date: 09 Nov 2007
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Biophysical, Chemical, and Functional Probes of R...

Editor: Daniel Herschlag Release Date: 09 Dec 2009
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Globins and Other Nitric Oxide-Reactive Proteins,...

Editor: Robert K. Poole Release Date: 22 Apr 2008
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Osmosensing and Osmosignaling

Editors: Helmut Sies & Dieter Haeussinger Release Date: 01 Oct 2007
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Thiol Redox Transitions in Cell Signaling, Part A...

Editors: Enrique Cadenas & Lester Packer Release Date: 14 Jun 2010
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Liposomes, Part G

Editor: Nejat Duzgunes Release Date: 19 Nov 2009
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RNA Editing

Editor: Jonatha Gott Release Date: 01 Aug 2007
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Chemokines, Part B

Editors: Tracy Handel & Damon Hamel Release Date: 12 Jun 2009
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Cryo-EM Part A: Sample Preparation and Data Colle...

Editor: Grant Jensen Release Date: 14 Oct 2010
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Two-Component Signaling Systems, Part A

Editors: Melvin Simon & Brian Crane & Alexandrine Crane Release Date: 03 Jul 2007
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RNA Modification

Editor: Jonatha Gott Release Date: 01 Aug 2007
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Chemokines, Part A

Editors: Tracy Handel & Damon Hamel Release Date: 27 May 2009
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Biophysical, Chemical, and Functional Probes of R...

Editor: Daniel Herschlag Release Date: 24 Nov 2009
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Single Molecule Tools, Part B: Super-Resolution, ...

Editor: Nils Walter Release Date: 02 Aug 2010
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Oxygen Biology and Hypoxia

Editors: Helmut Sies & Bernard Bruene Release Date: 08 Nov 2007
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Cryo-EM Part B: 3-D Reconstruction

Editor: Grant Jensen Release Date: 14 Oct 2010
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Integrins

Editor: David Cheresh Release Date: 27 Aug 2007
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Complex enzymes in microbial natural product bios...

Editor: David Hopwood Release Date: 24 Apr 2009
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Translation Initiation: Reconstituted Systems an...

Editor: Jon Lorsch Release Date: 09 Oct 2007
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Biothermodynamics, Part B

Editors: Michael Johnson & Jo Holt & Gary Ackers Release Date: 24 Nov 2009
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Fluorescence Spectroscopy

Editors: Ludwig Brand & Michael Johnson Release Date: 11 Dec 2008
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Single Molecule Tools, Part A: Fluorescence Based...

Editor: Nils Walter Release Date: 14 Jun 2010
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Angiogenesis: In Vivo Systems, Part A

Editor: David Cheresh Release Date: 29 Oct 2008
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Complex enzymes in microbial natural product bios...

Editor: David Hopwood Release Date: 24 Apr 2009
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Computer Methods Part A

Editors: Michael Johnson & Ludwig Brand Release Date: 30 Jan 2009
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Thiol Redox Transitions in Cell Signaling, Part B

Editors: Enrique Cadenas & Lester Packer Release Date: 08 Jul 2010
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Constitutive activity in receptors and other Prot...

Editor: Melvin Simon Release Date: 15 Nov 2010
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Liposomes, Part F

Editor: Nejat Duzgunes Release Date: 19 Nov 2009
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Lipidomics and Bioactive Lipids: Mass Spectromet...

Editor: H. Alex Brown Release Date: 26 Nov 2007
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Lipidomics and Bioactive Lipids: Lipids and Cell...

Editor: H. Alex Brown Release Date: 12 Nov 2007
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Autophagy in Mammalian Systems, Part B

Editor: Daniel Klionsky Release Date: 27 Jan 2009
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MicroRNA Methods

Editor: John Rossi Release Date: 30 Aug 2007
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Autophagy in Disease and Clinical Applications, P...

Editor: Daniel Klionsky Release Date: 11 Feb 2009
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Cumulative Subject Index

Editor: John Abelson Release Date: 27 Nov 2002
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Guide to Yeast Genetics and Molecular and Cell Bi...

Editor: UNKNOWN AUTHOR Release Date: 18 Jun 2002
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Numerical Computer Methods, Part C

Editors: Michael Johnson & Ludwig Brand Release Date: 29 Jun 2000
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Regulators of G Protein Signalling, Part A

Editor: David Siderovski Release Date: 19 Aug 2004
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Branched-Chain Amino Acids, Part B

Editors: John Sokatch & Robert Harris Release Date: 25 Aug 2000
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Nitric Oxide, Part D

Editors: Enrique Cadenas & Lester Packer Release Date: 21 Nov 2002
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Regulators of G Protein Signalling, Part B

Editor: David Siderovski Release Date: 12 Oct 2004
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Redox Cell Biology and Genetics, Part B

Editors: Chandan Sen & Lester Packer Release Date: 06 Jun 2002
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Flavonoids and Other Polyphenols, Methods in Enzy...

Editors: Lester Packer & Helmut Sies Release Date: 25 May 2001
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Ubiquitin and Protein Degradation, Part B

Editor: Raymond Deshaies Release Date: 24 Oct 2005
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Functional Glycomics

Editor: Minoru Fukuda Release Date: 21 Nov 2006
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Glycobiology

Editor: Minoru Fukuda Release Date: 01 Nov 2006
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Chromatin and Chromatin Remodeling Enzymes Part C

Authors: Carl Wu & C. Allis Release Date: 30 Jan 2004
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Ribonucleases, Part A: Functional Roles and Mecha...

Editor: Allen Nicholson Release Date: 18 Sep 2001
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Ribonucleases, Part B: Artificial and Engineered ...

Editor: Allen Nicholson Release Date: 21 Sep 2001
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Regulators and Effectors of Small GTPases: Ras Fa...

Editors: W. Balch & Channing Der & Alan Hall Release Date: 07 Apr 2006
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DNA Microarrays, Part B: Databases and Statistics

Editors: Alan Kimmel & Brian Oliver Release Date: 28 Aug 2006
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Quinones and Quinone Enzymes, Part B

Editors: Helmut Sies & Lester Packer Release Date: 20 Feb 2004
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Liposomes, Part E

Editor: Nejat Duzgunes Release Date: 10 Feb 2005
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Recognition of Carbohydrates in Biological System...

Authors: Y. Lee & Reiko Lee Release Date: 12 Aug 2003
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Guide to Yeast Genetics and Molecular Cell Biolog...

Editors: Christine Guthrie & Gerald Fink Release Date: 31 May 2002
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Microbial Growth in Biofilms, Part A: Development...

Editor: Ron Doyle Release Date: 25 May 2001
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Singlet Oxygen, UV-A and Ozone

Editors: Lester Packer & Helmut Sies Release Date: 27 Jun 2000
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Molecular Evolution, Producing the Biochemical Da...

Editors: Elizabeth Zimmer & Eric Roalson Release Date: 31 May 2005
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Energetics of Biological Macromolecules, Part E

Editors: Jo Holt & Michael Johnson & Gary Ackers Release Date: 05 Mar 2004
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Numerical Computer Methods, Part D

Editors: Ludwig Brand & Michael Johnson Release Date: 26 Mar 2004
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Protein Phosphatases

Authors: Susanne Klumpp & Josef Krieglstein Release Date: 12 Dec 2003
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Hyperthermophilic Enzymes, Part B

Editors: Michael Adams & Roger Kelly Release Date: 07 Mar 2001
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Enzyme Kinetics and Mechanism, Part F: Detection ...

Author: Daniel Purich Release Date: 21 Oct 2002
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Regulators and Effectors of Small GTPases: Rho F...

Editors: W. Balch & Channing Der & Alan Hall Release Date: 07 Feb 2006
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Liposomes, Part A

Editor: Nejat Duzgunes Release Date: 27 Oct 2003
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Confocal Microscopy

Editor: P. Michael Conn Release Date: 24 Aug 1999
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Gene Therapy Methods

Editor: M. Ian Phillips Release Date: 22 Feb 2002
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Imaging in Biological Research, Part B

Editor: P. Michael Conn Release Date: 14 May 2004
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Liposomes, Part D

Editor: Nejat Duzgunes Release Date: 14 Jun 2004
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Adult Stem Cells

Editors: Irina Klimanskaya & Robert Lanza Release Date: 22 Nov 2006
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Cytochrome P450, Part C, Methods in Enzymology

Editors: Eric Johnson & Michael Waterman Release Date: 25 Oct 2002
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DNA Microarrays Part A: Array Platforms & Wet-Be...

Editors: Alan Kimmel & Brian Oliver Release Date: 28 Aug 2006
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Stem Cell Tools and Other Experimental Protocols

Editors: Robert Lanza & Irina Klimanskaya Release Date: 12 Dec 2006
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Glycomics

Editor: Minoru Fukuda Release Date: 26 Oct 2006
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DNA Repair, Part B

Editors: Judith Campbell & Paul Modrich Release Date: 01 May 2006
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Sphingolipid Metabolism and Cell Signaling, Part B

Editors: Alfred Merrill, Jr. & Yusuf Hannun Release Date: 16 Oct 2000
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G Protein Pathways, Part A: Receptors

Editors: Ravi Iyengar & John Hildebrandt Release Date: 03 Oct 2001
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Laser Capture in Microscopy and Microdissection, ...

Editor: P. Michael Conn Release Date: 21 Oct 2002
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Chromatin and Chromatin Remodeling Enzymes, Part B

Authors: Carl Wu & C. Allis Release Date: 11 Feb 2004
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Cumulative Subject Index

Editors: John Abelson & Melvin Simon Release Date: 18 Oct 2000
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