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Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging… Read more
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Contributors
Preface
Chapter One. Folate and B12 in Prostate Cancer
Abstract
Abbreviations
1 Introduction
2 Prostate Cancer
3 Folate, B12, and One-Carbon Metabolism
4 Pathways and Mechanisms
5 Folate and Prostate Cancer
6 Vitamin B12 and Prostate Cancer
7 Homocysteine, Methionine, and Betaine
8 Folic Acid and B12 Supplements
9 Genetic Epidemiology
10 Conclusions
Acknowledgment
References
Chapter Two. Mismatch Repair Proteins in Recurrent Prostate Cancer
Abstract
Abbreviations
1 Mismatch Repair Proteins in Repair
2 MMR Proteins in DNA Damage Response
3 MMR Proteins in Cancer
4 MMR Proteins in Prostate Carcinogenesis
5 MMR Proteins: Role in Treatment Response?
6 Conclusions
Acknowledgments
References
Chapter Three. Protein Antioxidants in Thalassemia
Abstract
1 Introduction
2 Normal Iron Metabolism
3 Iron Metabolism in Thalassemia
4 Oxidative Stress in Thalassemia
5 Antioxidative Status in Thalassemia
6 Antioxidative Therapeutic Trials
7 Future Directions and Concluding Remarks
Acknowledgments and Conflict of Interest
References
Chapter Four. Immune Complexome Analysis
Abstract
Abbreviations
1 Immune Complex
2 Identification of Disease-Associated Antigens
3 Immune Complexome Analysis of RA Patients
4 Conclusion
References
Chapter Five. Genetics of Gallstone Disease
Abstract
Abbreviations
1 Genetic Background of Human Cholesterol Gallstones
2 Pathophysiology of Gallstone Formation
3 Candidate Genes Involved in Regulation of Biliary Cholesterol Secretion
4 Mucin Gene
5 Gallbladder Motility
6 Conclusion
References
Chapter Six. Glycoprotein 2 Antibodies in Crohn’s Disease
Abstract
Abbreviations
1 Crohn’s Disease and Pancreatic Autoreactivity
2 Identification of GP2 as the Main Autoantigenic Target of PAB
3 Biochemistry of Glycoprotein 2
4 Physiology of Glycoprotein 2
5 Possible Role of Glycoprotein 2 in Pathophysiology
6 Anti-GP2 Autoantibodies in the Serology of IBD
References
Index
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