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Chemokines, Part A
1st Edition, Volume 460 - May 16, 2009
Editors: Tracy Handel, Damon Hamel
Language: English
Hardback ISBN:9780123749086
9 7 8 - 0 - 1 2 - 3 7 4 9 0 8 - 6
eBook ISBN:9780080956978
9 7 8 - 0 - 0 8 - 0 9 5 6 9 7 - 8
The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human…Read more
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The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human diseases and infections, including certain types of cancer, inflammatory diseases, HIV, and malaria. This volume, focusing on chemokines as potential targets for disease intervention, and its companion volume (Methods in Enzymology volume 462, focusing on chemokine structure and function, as well as signaling) provide a comprehensive overview and time-tested protocols in this field, making it an essential reference for researchers in the area.
Along with its companion volume, provides a comprehensive overview of chemokine methods, specifically as related to potential disease therapy
Gathers tried, tested, and trusted methods and techniques from top players in chemokine research
Provides an essential reference for researchers in the field
Researchers in cell, molecular and developmental biology; biochemists pharmacologists, and geneticists
1. Chemokines in human breast tumor cells: modifying their expression levels and determining their effects on the malignancy phenotype (Adit Ben-Baruch)
2. Chemokines and Receptors in Neuroinflammation (Richard Ransohoff)
3. The use of receptor homology modeling to facilitate the design of selective chemokine receptor ligands (Percy Carter and Andrew J Tebben)
4. CXCR4 and Mobilization of Hemopoietic Precursors (John Dispersio)
5. Chemokines and the Role of the Microenvironment in Cancer (Alberto Mantovani)
6. Design and Development of Maraviroc, An Antagonist of CCR5 for the Treatment of HIV (Eina Van Der Ryst) CHEMOKINE RELATED PROTEINS FROM PATHOGENS--THERAPEUTIC TARGETS OR POTENTIAL THERAPEUTICS
7. Chemokine Binding Proteins from Herpesviruses (Antonio Alcami)