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Advances in Carbohydrate Chemistry and Biochemistry
1st Edition, Volume 67 - July 13, 2012
Editor: Derek Horton
Language: English
Hardback ISBN:9780123965271
9 7 8 - 0 - 1 2 - 3 9 6 5 2 7 - 1
eBook ISBN:9780123965073
9 7 8 - 0 - 1 2 - 3 9 6 5 0 7 - 3
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological as…Read more
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Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.
Contributions from leading authorities
Informs and updates on all the latest developments in the field
Researchers in biochemistry, organic chemistry, medicinal chemistry and instrumentation methodology
Contributors to Volume 383
Preface
Nathan Sharon
The Early Years
Love Affair with Soybean Agglutinin and Other Lectins
Biological Effects of Plant Lectins
Lectins as Tools for the Study of Membranes and Separations of Cells
Lectins Involved in Host—Microbial Recognitions
Animal Lectins in Cell Recognition
Teacher, Educator, Collector, Swimmer, and Curious Traveler
Chapter 2 Combining Computational Chemistry and Crystallography for a Better Understanding of the Structure of Cellulose
I Introduction
II Information from Crystals of Related Small Molecules
III Energy Calculations
IV Detection of New Stabilizing Interactions in Cellulose with Atoms-in-Molecules Theory
V Modeling Crystals of Cellulose
VI Conclusions
Appendix Molecular Structure Drawings for Saccharide Analogues Having β-(1 → 4) Linkages
Chapter 3 Strategies in Synthesis of Heparin/Heparan Sulfate Oligosaccharides
I Introduction
II Linear Synthesis
III Active–Latent Glycosylation Strategy
IV Selective Activation
V Reactivity-Based Chemoselective Glycosylation
VI Reactivity-Independent, Pre-Activation-Based, Chemoselective Glycosylation
VII Chemoenzymatic Synthesis
VIII Future Outlook
Chapter 4 Chemical Synthesis of Glycosylphosphatidylinositol Anchors
I Introduction
II Classic Approaches to GPI Synthesis
III Diversity-Oriented Approaches to GPI Synthesis
IV Conclusions and Outlook
Chapter 5 Effect of Protein Dynamics and Solvent in Ligand Recognition by Promiscuous Aminoglycoside-Modifying Enzymes
I Introduction
II Aminoglycoside Antibiotics
III Aminoglycoside-Modifying Enzymes
IV Thermodynamic Properties of Enzyme–AG Complexes
V Protein Dynamics in Substrate Recognition and Substrate Promiscuity of AGMEs
VI Conclusions and Future Considerations
Author Index
Subject Index
No. of pages: 290
Language: English
Edition: 1
Volume: 67
Published: July 13, 2012
Imprint: Academic Press
Hardback ISBN: 9780123965271
eBook ISBN: 9780123965073
DH
Derek Horton
Affiliations and expertise
The American University, Washington, DC, USA
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