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Linkage Thermodynamics of Macromolecular Interactions
1st Edition, Volume 51 - May 20, 1998
Editors: Enrico Di Cera, Frederic M. Richards, David S. Eisenberg, Peter S. Kim
Language: English
Hardback ISBN:9780120342518
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eBook ISBN:9780080582245
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This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage…Read more
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This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.
M. Schaefer, H. van Vlijmen, and M. Karplus, Electrostatic Contributions to Molecular Free Energies in Solution. E. Di Cera, Site-Specific Analysis of Mutational Effects in Proteins. S.J. Edelstein and J.-P. Changeux, Allosteric Transitions of the Acetylcholine Receptor. G.K. Ackers, Deciphering the Molecular Code of Hemoglobin Allostery. E. Freire, Statistical Thermodynamic Linkage between Conformational and Binding Equilibria. M.T. Record, Jr., W. Zhang, and C.F. Anderson, Analysis of the Effects of Salts and Uncharged Solutes on Protein and Nucleic Acid Equilibria and Processes: A Practical Guide to Recognizing and Interpreting Polyelectrolyte Effects, Hofmeister Effects, and Osmotic Effects of Salts. S.N. Timasheff, Control of Protein Stability and Reactions by Weakly Interacting Cosolvents: The Simplicity of the Complicated. Author Index. Subject Index.
No. of pages: 473
Language: English
Edition: 1
Volume: 51
Published: May 20, 1998
Imprint: Academic Press
Hardback ISBN: 9780120342518
eBook ISBN: 9780080582245
ED
Enrico Di Cera
Affiliations and expertise
Washington University School of Medicine, St. Louis, Missouri, U.S.A.
FR
Frederic M. Richards
Affiliations and expertise
Yale University, New Haven, Connecticut, U.S.A.
DE
David S. Eisenberg
Affiliations and expertise
University of California, Los Angeles, U.S.A.
PK
Peter S. Kim
Affiliations and expertise
Massachusetts Institute of Technology, Whitehead Institute for Biomedical Research, Howard Hughes Medical Institute Research Laboratories, Cambridge, U.S.A.
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