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Immunopathogenesis of Type 1 Diabetes Mellitus
1st Edition, Volume 100 - November 25, 2008
Editor: Frederick W. Alt
Language: English
Hardback ISBN:9780123743268
9 7 8 - 0 - 1 2 - 3 7 4 3 2 6 - 8
eBook ISBN:9780080921730
9 7 8 - 0 - 0 8 - 0 9 2 1 7 3 - 0
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. This thematic volume…Read more
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Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. This thematic volume focuses on the immunopathogenesis of type 1 diabetes mellitus. Edited and authored by the foremost scientists in this field, it provides up-to-date information and directions for future research.
Immunologists and infectious disease specialists, cell biologists and hematologists
1. Introduction
Hugh McDevitt and Emil R. Unanue
2. TBC
Harald von Boehmer and Elmar Jaeckel
3. TBC
Lucienne Chatenoud
4. TBC
Ake Lernmark
5. Untitled
Dianne Mathis
6. CD8+ T cells in Type 1 Diabetes
Pere Santamaria
7. Dysregulation of T cell Peripheral Tolerance in Type 1 Diabetes
Roland Tisch
8. Genetic Basis for Protection from Type 1 Diabetes
Linda Wicker
No. of pages: 300
Language: English
Edition: 1
Volume: 100
Published: November 25, 2008
Imprint: Academic Press
Hardback ISBN: 9780123743268
eBook ISBN: 9780080921730
FA
Frederick W. Alt
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA
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