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Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wi… Read more
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Series Page
Contributors
Chapter One. Fate Determination of Mature Autoreactive B Cells
1 Introduction
2 Formation of the Naive B Cell Repertoire
3 B Cell Activation
4 The Cellular Composition of GC
5 The GC Response
6 Regulating Autoreactivity Within the GC
7 Cellular Mediators of GC Selection
8 Regulation of Plasma Cells
9 Conclusion
References
Chapter Two. Epigenetic Control of Cytokine Gene Expression: Regulation of the TNF/LT Locus and T Helper Cell Differentiation
1 The Components of Epigenetic Transcriptional Regulation
2 Cytokine Gene Regulation
3 Perspectives and Future Directions
References
Chapter Three. Autoimmunity in Rheumatoid Arthritis: Citrulline Immunity and Beyond
1 Introduction
2 Present State of the Art Concerning Genes, Environment, and Anticitrulline Immunity in RA
3 Unresolved Issues Concerning the Specificity and Genetic Basis of Autoimmune Reactions in RA: Focus on the Heterogeneity of the RA Syndrome
4 Unresolved Issues Concerning the Triggering of Various Autoimmune Reactions in RA: Focus on Events Outside the Joints
5 Unresolved Issues Concerning the Contributions of Various Autoimmune Reactions to Symptoms of RA: Focus on Events in Joints and in Sites of Extra-Articular Manifestations of RA
6 Conclusions Concerning Research Strategies and Efforts to Turn the Emerging Insights of Adaptive Immunity in RA into Personalized Prevention and Therapy
References
Index
Contents of Recent Volumes
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