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Advances in Clinical Chemistry
1st Edition, Volume 62 - November 28, 2013
Editor: Gregory S. Makowski
Language: English
Hardback ISBN:9780128000960
9 7 8 - 0 - 1 2 - 8 0 0 0 9 6 - 0
eBook ISBN:9780128002926
9 7 8 - 0 - 1 2 - 8 0 0 2 9 2 - 6
Volume 62 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research…Read more
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Volume 62 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.
Expertise of international contributors
Latest cutting-edge technologies
Comprehensive in scope
Clinical Laboratory Professionals, Physicians and Research Scientists
Contributors
Preface
Chapter One. Myeloperoxidase in Cardiovascular Disease
Abstract
Abbreviations
1 Introduction
2 MPO Expression and Structure
3 MPO Enzymatic Activities
4 MPO and Cardiovascular Diseases
5 Challenges of MPO as a Clinical Biomarker
6 Conclusion
Acknowledgments
References
Chapter Two. Biomarkers of Liver Fibrosis
Abstract
Abbreviations
1 Introduction
2 Biomarkers of Liver Fibrosis
3 Noninvasive Biomarkers of Liver Fibrosis
4 Biomarkers of Liver Fibrosis in Chronic Hepatitis C
5 Biomarkers of Liver Fibrosis in Chronic Hepatitis B
6 Biomarkers of Liver Fibrosis in Nonalcoholic Fatty Liver Disease
7 Biomarkers of Liver Fibrosis in Alcoholic Liver Disease
8 Conclusion
References
Chapter Three. Keratin 18 and Heat-Shock Protein in Chronic Kidney Disease
Abstract
1 Introduction
2 Cell Death
3 K-18 in CKD
4 The Heat-Shock Response in CKD
5 Conclusion
References
Chapter Four. Tear Fluid Protein Biomarkers
Abstract
Abbreviations
1 The Tear Film
2 Secretion and Structure of Tear Film
3 Types of Tears and Collection Methods
4 Tears as a Potential Source of Biomarkers
5 Tear Biomarkers Identified Using Proteomics
6 Proteomics for Tear Biomarker Detection
7 Challenges in Tear Biomarker Research
8 Conclusions and Future Directions
Acknowledgments
References
Chapter Five. Urinary mRNA in Systemic Lupus Erythematosus
Abstract
1 Introduction
2 Urinary Messenger RNA Expression Study
3 Pathogenesis and Target Selection
4 Applications in Lupus Nephritis
5 Future Directions
6 Summary
Acknowledgment
References
Chapter Six. microRNA in Gastrointestinal Cancer: A Step Closer to Reality
Abstract
Abbreviations
1 Introduction
2 Methodology
3 Biogenesis and Function of microRNAs
4 microRNA and Cancer
5 microRNA as Noninvasive Biomarkers
6 microRNAs as Noninvasive Biomarkers in Gastrointestinal Cancer
7 Potential Limitations and Open Questions for Current Generation of miRNA Biomarkers
8 Concluding Remarks and Perspectives
Acknowledgments
References
Chapter Seven. Marine Sulfated Glycans with Serpin-Unrelated Anticoagulant Properties
Abstract
1 Marine Sulfated Polysaccharides of Unique and Regular Structures
2 MSP and Anticoagulation
3 The Uncommon Serpin-Independent Anticoagulant Mechanism
4 Advantages of FucCS and SG in Medicine
References
Index
No. of pages: 328
Language: English
Edition: 1
Volume: 62
Published: November 28, 2013
Imprint: Academic Press
Hardback ISBN: 9780128000960
eBook ISBN: 9780128002926
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in his joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President and Chief Scientific Officer for Clinical Laboratory Partners in Newington CT, USA.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USA
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