Nitric Oxide, 1st Edition

Nitric Oxide, 1st Edition,Bruno Tota,Barry Trimmer,ISBN9780444531193

Tota   &   Trimmer   

Elsevier Science




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This volume provides a novel insight to the evolutionary and comparative aspects of nitric oxide- nitric oxide synthase system as a central regulator of invertebrate and vertebrate homeostasis. By critically selecting and summarizing the ever-increasing number of original studies, these presentations review a variety of important signalling and modulatory roles played by nitric oxide at molecular, cell, organ and organ system levels. It addresses not only specialists and graduate students in the field, but also all biologists concerned with how this unique, gaseous, pleiotropic molecule has been employed by living systems, uncovering a new dimension of the wonders of life.


Experimental biologists, researchers in developmental cell and comparative biology within animal and plant biology.

Bruno Tota

Affiliations and Expertise

Universita della Calabria, Arcavacata de Rende, Italy

Barry Trimmer

Affiliations and Expertise

Tufts University School of Medicine, Boston, MA, USA

Nitric Oxide, 1st Edition

1. On the Comparative Biology of NO Synthetic Pathways: Parallel Evolution of NO-Mediated Signaling

Leonid L. Moroz and Andrea B. Kohn

2. Nitric Oxide Biogenesis, Signalling and Roles in Molluscs: The Sepia officinalis Paradigm

Anna Palumbo and Marco d’Ischia

3. Soluble Guanylyl Cyclases in Invertebrates: Targets for NO and O2

David B. Morton and Anke Vermehren

4. Nitric Oxide Signalling in Insect Epithelial Transport

Shireen-A. Davies

5. Nitric Oxide/Cyclic GMP Signaling and Insect Behavior

Ralf Heinrich and Geoffrey K. Ganter

6. Impact of Nitrative/Nitrosative Stress in Mitochondria: Unraveling Targets for Malaria Chemotherapy

Shirley Luckhart, Kazunobu Kato and Cecilia Giulivi

7. Effects of S-Nitrosation of Nitric Oxide Synthase

Douglas A. Mitchell, Thomas Michel and Michael A. Marletta

8. Regulatory Role and Evolution of Unconventional NOS-Related RNAs

Sergei Korneev and Michael O’Shea

9. The Role of Blood Nitrite in the Control of Hypoxic Vasodilation

Angela Fago and Frank B. Jensen

10. Nitrite is a Vascular Store of NO which Mediates Hypoxic Signaling and Protects against Ischemia/Reperfusion Injury

Cameron Dezfulian, Mark T. Gladwin and Sruti Shiva

11. Nitric Oxide and the Zebrafish (Danio rerio): Developmental Neurobiology and Brain Neurogenesis

Bo Holmqvist, Lars Ebbesson and Per Alm

12. NO in the Development of Fish

Bernd Pelster

13. Role of Nitric Oxide in Vascular Regulation in Fish

Claudio Agnisola and Daniela Pellegrino

14. NOS Distribution and NO Control of Cardiac Performance in Fish and Amphibian Hearts

Bruno Tota, Sandra Imbrogno, Rosa Mazza and Alfonsina Gattuso

15. Nitric Oxide and Histamine in Hibernation and Neuroprotection

Pertti Panula, Giuseppina Giusi, Rosa Maria Facciolo, Tina Sallmen, Minamaija Lintunen and Marcello Canonaco

16. Nitric Oxide, Peroxynitrite and Matrix Metalloproteinases: Insight into the Pathogenesis of Sepsis

Jonathan Cena, Ava K. Chow and Richard Schulz

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