Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases

Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases, 1st Edition

Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases, 1st Edition,Narenda Kumar,Rajiv Kumar,ISBN9780323264334


William Andrew




Demystifies new nanomedicine applications for the treatment of the main life-threatening disease groups: cancers, neurological disorders, cardiovascular diseases, gastrointestinal diseases and HIV/AIDS

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Key Features

  • Gain an understanding of how nanotechnologies and nanomaterials can be deployed in the fight against the major life-threatening diseases: cancer, neurological disorders (including Alzheimer's and Parkinson's), cardiovascular diseases, and HIV/AIDS
  • Discover the latest developments in nanomedicine, from therapies and drug delivery to diagnostics and disease prevention
  • The authors cover the health risks of nanomaterials as well as their benefits, considering toxicity and potential carcinogens


Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases takes a scientific approach to nanotechnology and nanomaterials applications in medicine, while also explaining the core biological principles for an audience of biomedical engineers, materials scientists, pharmacologists, and medical diagnostic technicians. The book is structured by major disease groups, offering a practical, application-based focus for scientists, engineers, and clinicians alike. The spectrum of medical applications is explored, from diagnostics and imaging to drug delivery, monitoring, therapies, and disease prevention. It also focuses specifically on the synthesis of nanomaterials and their potential health risks (particularly toxicity).

Nanomedicine — the application of nanomaterials and devices for addressing medical problems — has demonstrated great potential for enabling improved diagnosis, treatment, and  monitoring of many serious illnesses, including cancer, cardiovascular and neurological disorders, HIV/AIDS, and diabetes, as well as many types of inflammatory and infectious diseases.


Biomedical Engineers, Pharmacologists / Drug Design, Chemists, Materials Scientists, Medical Researchers, Clinicians

Narenda Kumar

Affiliations and Expertise

Former Director, Defence Laboratory, Jodhpur, DRDO, Ministry of Defence, India

Rajiv Kumar

Affiliations and Expertise

Assistant Professor, Dept of Chemistry, Shivaji College, University of Delhi

Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases, 1st Edition

  • Preface
  • Acknowledgments
  • Chapter 1. Introduction
    • Abstract
    • 1.1 Nanoscience and nanotechnology
    • 1.2 Building blocks of the human body system
    • 1.3 Bio-chemical functions of organic matters
    • 1.4 Cellular system of the human body
    • 1.5 Membranes
    • 1.6 Cellular functions and metabolism
    • 1.7 Organs, organ systems, and their level of organization
    • 1.8 Nanomedicine
    • 1.8.2 Nanoparticles as a drug delivery system
    • 1.9 Regenerative medicine
    • 1.10 Current challenges
    • 1.11 Regulatory and risk issues
    • 1.12 Future outlook
    • References
  • Chapter 2. Nano-based Drug Delivery and Diagnostic Systems
    • Abstract
    • 2.1 Introduction
    • 2.2 Nanoparticles-based drug delivery system
    • 2.3 Delivery of RNA/DNA
    • 2.4 In vitro effects of particle size and shape of nanocarrier particles on drug delivery
    • 2.5 Pharmacokinetic of nanoparticles (NPs)
    • 2.6 Physicochemical characteristics of NPs
    • 2.7 Organ clearance of nanomaterials
    • 2.8 Nanodiagnostic tools
    • References
  • Chapter 3. Nanomedicine for Neurological Disorder
    • Abstract
    • 3.1 Introduction
    • 3.2 Chemistry of nanotransmitters and modulators
    • 3.3 Neurological diseases
    • 3.4 Diagnostic test for neurological disorder
    • 3.5 Therapies for neurological disorders
    • 3.6 Nanomedicine for neurological disorders
    • 3.7 Challenges and future prospective
    • References
  • Chapter 4. Nanomedicine for Cancer Treatment
    • Abstract:
    • 4.1 Introduction
    • 4.2 Causes and mechanisms for occurrence of cancer
    • 4.3 Viruses and cancer
    • 4.4 Angiogenesis in cancer
    • 4.5 Classification of cancer
    • 4.6 Detection and diagnosis of cancer
    • 4.7 Modalities for cancer treatment
    • 4.8 Nanomedicine for the treatment of cancer
    • 4.9 Shell cross-linked KNEDEL-LIKE nanoparticles (SCKs) as emerging drug carriers
    • References
  • Chapter 5. Nanomedicine for Treatment of Cardiovascular Diseases and Stroke
    • Abstract:
    • 5.1 Introduction
    • 5.2 Diagnostic and treatment of CVDs
    • 5.3 Nanomedicine in diagnosis and treatment of cardiovascular diseases (CVD)
    • 5.4 Stem cell therapy
    • 5.5 Cardiac graft
    • References
  • Chapter 6. Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS)
    • Abstract
    • 6.1 Introduction
    • 6.2 HIV pathology
    • 6.3 HIV infection and the body’s response
    • 6.4 Mechanism of infection
    • 6.5 Diagnosis of HIV and AIDS
    • 6.6 Prevention, cure, and current treatment for HIV/AIDS
    • 6.7 Nanotechnology for treatment of HIV/AIDS
    • 6.8 HIV protection
    • References
  • Chapter 7. Nanomedicine for Gastrointestinal Diseases
    • Abstract:
    • 7.1 Introduction
    • 7.2 GI disorder
    • 7.3 Gastrointestinal disease caused by internal permeability
    • 7.4 Gastrointestinal stromal tumor (GIST)
    • 7.5 Gastroparesis
    • 7.6 Nanomaterials for treatment of gastrointestinal disease
    • 7.7 Application of nanomedicine in gastroenterology; specific examples
    • 7.8 Nanotechnology and gastrointestinal endoscopy: nanopowder as hemostatic agent in gastric ulcer bleed
    • References
  • Index
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