Methods in Enzymology

The critically acclaimed laboratory standard for almost 50 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 500 volumes the series contains much material still relevant today and is truly an essential publication for researchers in all fields of life sciences, including microbiology, biochemistry, cancer research and genetics-just to name a few. Five of the 2013 Nobel Laureates have edited or contributed to volumes of MIE.

About the Editors: John N. Abelson, California Institute of Technology, Division of Biology, Pasadena, USA; and Melvin I. Simon, California Institute of Technology, Division of Biology, Pasadena, USA

Impact Factor 2012: 2.002 (Copyright ISI Journal Citation Report)

Praise for the Series: "Should be on the shelves of all libraries in the world as a whole collection." - CHEMISTRY IN INDUSTRY "The work most often consulted in the lab." - ENZYMOLOGIA “The Methods in Enzymology series represents the gold-standard." - NEUROSCIENCE

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Protein Kinase Inhibitors in Research and Medicin...

Editor: Kevan Shokat Release Date: 01 Dec 2014
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Protein Kinase Inhibitors in Research and Medicine

Editor: Kevan Shokat Release Date: 14 Nov 2014
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Regulated Cell Death Part A , Apoptotic Mechanisms

Editors: Avi Ashkenazi & Junying Yuan & Jim Wells Release Date: 24 Jun 2014
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Regulated Cell Death Part B, Necroptotic, Autopha...

Editors: Avi Ashkenazi & Jim Wells & Junying Yuan Release Date: 23 Jul 2014
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Conceptual Background and Bioenergetic/Mitochondr...

Editors: Lorenzo Galluzzi & Guido Kroemer Release Date: 27 May 2014
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Reconstituting the Cytoskeleton

Editor: Ron Vale Release Date: 27 Mar 2014
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Cell-wide Metabolic Alterations Associated With M...

Editors: Lorenzo Galluzzi & Guido Kroemer Release Date: 16 Jun 2014
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Endosome Signalling Part A

Editor: P. Michael Conn Release Date: 13 Jan 2014
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Research Methods in BIomineralization Science

Editor: Jim De Yoreo Release Date: 15 Nov 2013
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Laboratory Methods in Enzymology: RNA

Author: Jon Lorsch Release Date: 24 Sep 2013
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Methods of Adipose Tissue Biology Part A

Editor: Ormond Macdougald Release Date: 07 Feb 2014
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Laboratory Methods in Enzymology: Cell, Lipid and...

Editor: Jon Lorsch Release Date: 12 Nov 2013
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Endosome Signalling Part B

Editor: P. Michael Conn Release Date: 14 Jan 2014
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Laboratory Methods in Enzymology: DNA

Editor: Jon Lorsch Release Date: 23 Sep 2013
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Microbial Metagenomics, Metatranscriptomics, and ...

Editor: Ed DeLong Release Date: 08 Oct 2013
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Laboratory Methods in Enzymology: Protein Part A

Editor: Jon Lorsch Release Date: 31 Jan 2014
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Natural Product Biosynthesis by Microorganisms an...

Editor: David Hopwood Release Date: 01 Oct 2012
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Natural Product Biosynthesis by Microorganisms an...

Editor: David Hopwood Release Date: 17 Oct 2012
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Cilia, Part B

Editor: Wallace F. Marshall Release Date: 16 Apr 2013
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Fluorescence Fluctuation Spectroscopy (FFS), Part...

Editor: Sergey Tetin Release Date: 15 Jan 2013
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Natural Product Biosynthesis by Microorganisms an...

Editor: David Hopwood Release Date: 01 Nov 2012
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Fluorescence Fluctuation Spectroscopy (FFS) Part B

Editor: Sergey Tetin Release Date: 18 Jan 2013
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Methods in Protein Design

Editor: Amy Keating Release Date: 12 Mar 2013
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G Protein Coupled Receptors, Modeling, Activation...

Editor: P. Michael Conn Release Date: 22 Feb 2013
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Hydrogen Peroxide and Cell Signaling, Part B

Editors: Lester Packer & Enrique Cadenas Release Date: 15 Jul 2013
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Hydrogen Peroxide and Cell Signaling, Part A

Editors: Lester Packer & Enrique Cadenas Release Date: 08 Jul 2013
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Hydrogen Peroxide and Cell Signaling, Part C

Editors: Enrique Cadenas & Lester Packer Release Date: 29 Jul 2013
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Nucleosomes, Histones & Chromatin Part A

Editors: Carl Wu & C. Allis Release Date: 31 Aug 2012
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Nucleosomes, Histones & Chromatin Part B

Editors: Carl Wu & C. Allis Release Date: 10 Sep 2012
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Gene Transfer Vectors for Clinical Application

Editor: Theodore C. Friedman Release Date: 06 Mar 2012
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IMAGING AND SPECTROSCOPIC ANALYSIS OF LIVING CELL...

Editor: P. Michael Conn Release Date: 24 Jan 2012
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Protein Engineering for Therapeutics, Part B

Editors: K. Dane Wittrup & Gregory L. Verdine Release Date: 19 Jan 2012
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IMAGING AND SPECTROSCOPIC ANALYSIS OF LIVING CELL...

Editor: P. Michael Conn Release Date: 01 Feb 2012
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Cellulases

Editor: Harry Gilbert Release Date: 29 May 2012
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Nanomedicine, Cancer, Diabetes, and Cardiovascula...

Editor: Nejat Duzgunes Release Date: 30 Mar 2012
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Numerical Computer Methods, Part D

Editors: Ludwig Brand & Michael Johnson Release Date: 26 Mar 2004
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Fragment Based Drug Design, Tools, Practical Appr...

Editor: Lawrence Kuo Release Date: 09 Mar 2011
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The Unfolded Protein Response and Cellular Stress...

Editor: P. Michael Conn Release Date: 08 Feb 2011
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Serpin Structure and Evolution

Editors: James Whisstock & Phillip Bird Release Date: 16 Nov 2011
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Cryo-EM Part A: Sample Preparation and Data Colle...

Editor: Grant Jensen Release Date: 14 Oct 2010
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The Unfolded Protein Response and Cellular Stress...

Editor: P. Michael Conn Release Date: 08 Feb 2011
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Synthetic Biology, Part B, Computer Aided Design ...

Editor: Chris Voigt Release Date: 09 Jun 2011
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Constitutive activity in receptors and other Prot...

Editor: Melvin Simon Release Date: 15 Nov 2010
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Biothermodynamics, Part C

Editor: Melvin Simon Release Date: 12 Jan 2011
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The Unfolded Protein Response and Cellular Stress...

Editor: P. Michael Conn Release Date: 25 Feb 2011
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Research on Nitrification and Related Processes, ...

Editors: Martin Klotz & Lisa Stein Release Date: 04 May 2011
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Protein Engineering for Therapeutics, Part A

Editors: K. Dane Wittrup & Gregory L. Verdine Release Date: 11 Jan 2012
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Biothermodynamics, Part D

Editors: Michael Johnson & Jo Holt & Gary Ackers Release Date: 25 Feb 2011
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RNA helicases

Editor: Eckhard Jankowsky Release Date: 22 Jun 2012
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Research on Nitrification and Related Processes, ...

Editor: Martin Klotz Release Date: 10 Jan 2011
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Methods in Systems Biology

Editors: Hans Westerhoff & Malkhey Verma & Daniel Jameson Release Date: 26 Sep 2011
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IMAGING AND SPECTROSCOPIC ANALYSIS OF LIVING CELL...

Editor: P. Michael Conn Release Date: 24 Feb 2012
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Constitutive activity in receptors and other Prot...

Editor: Melvin Simon Release Date: 11 Nov 2010
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Nanomedicine, Infectious Diseases, Immunotherapy,...

Editor: Nejat Duzgunes Release Date: 23 May 2012
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Computer Methods, Part C

Editor: Melvin Simon Release Date: 12 Jan 2011
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Synthetic Biology, Part A, Methods for Part/Devic...

Editor: Chris Voigt Release Date: 23 May 2011
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Cryo-EM Part B: 3-D Reconstruction

Editor: Grant Jensen Release Date: 14 Oct 2010
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Biology of Serpins

Editors: James Whisstock & Phillip Bird Release Date: 18 Jul 2011
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Cryo-EM, Part C, Analyses, Interpretation, and Ca...

Editor: Grant Jensen Release Date: 14 Oct 2010
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Hormone Action, Part F: Protein Kinases

Editors: Jackie Corbin & Joel Hardman Release Date: 28 Sep 1983
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Drug and Enzyme Targeting, Part A, Volume 112: Dr...

Editors: Kenneth Widder & Ralph Green Release Date: 28 May 1985
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Steroids and Isoprenoids, Part B, Volume 111: Ste...

Editors: John Law & Hans Rilling Release Date: 28 Apr 1985
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Steroids and Isoprenoids, Part A, Volume 110: Ste...

Editors: John Law & Hans Rilling Release Date: 28 Mar 1985
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Enzyme Purification and Related Techniques, Part ...

Editor: William Jakoby Release Date: 28 Mar 1984
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Hormone Action, Part G: Calmodulin & Calcium-Bind...

Editors: Anthony Means & Bert O'Malley Release Date: 28 Sep 1983
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Cumulative Subject Index, Volume 120: Cumulative ...

Editors: Nathan Colowick & Nathan Kaplan Release Date: 28 Oct 1986
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Carbohydrate Metabolism, Part E, Volume 90: Carbo...

Editor: Willis Wood Release Date: 28 Nov 1982
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Cumulative Subject Index, Volume 95: Cumulative S...

Editors: Martha Dennis & Edward Dennis Release Date: 28 Feb 1986
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Polyamines, Volume 94: Polyamines

Editors: Herbert Tabor & Celia White Tabor Release Date: 28 Aug 1983
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Guide to Protein Purification, 2nd Edition

Editors: Richard Burgess & Murray Deutscher Release Date: 17 Nov 2009
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Angiogenesis: In Vitro Systems

Editor: David Cheresh Release Date: 02 Sep 2008
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Advanced Bacterial Genetics: Use of Transposons a...

Editor: Kelly Hughes Release Date: 27 Feb 2007
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RNA Editing

Editor: Jonatha Gott Release Date: 01 Aug 2007
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Small GTPases in Disease, Part B

Editors: W. Balch & Channing Der & Alan Hall Release Date: 01 Apr 2008
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Lipidomics and Bioactive Lipids: Lipids and Cell...

Editor: H. Alex Brown Release Date: 12 Nov 2007
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Biophysical, Chemical, and Functional Probes of R...

Editor: Daniel Herschlag Release Date: 09 Dec 2009
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Angiogenesis: In Vivo Systems, Part B

Editor: David Cheresh Release Date: 29 Oct 2008
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Translation Initiation: Reconstituted Systems an...

Editor: Jon Lorsch Release Date: 09 Oct 2007
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Glycobiology

Editor: Minoru Fukuda Release Date: 01 Nov 2006
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Autophagy in Disease and Clinical Applications, P...

Editor: Daniel Klionsky Release Date: 11 Feb 2009
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Biothermodynamics, Part B

Editors: Michael Johnson & Jo Holt & Gary Ackers Release Date: 24 Nov 2009
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Chemokines, Part B

Editors: Tracy Handel & Damon Hamel Release Date: 12 Jun 2009
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MicroRNA Methods

Editor: John Rossi Release Date: 30 Aug 2007
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Amyloid, Prions, and Other Protein Aggregates, Pa...

Editors: Ronald Wetzel & Indu Kheterpal Release Date: 06 Oct 2006
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Angiogenesis: In Vivo Systems, Part A

Editor: David Cheresh Release Date: 29 Oct 2008
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Complex enzymes in microbial natural product bios...

Editor: David Hopwood Release Date: 24 Apr 2009
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Globins and Other Nitric Oxide-Reactive Proteins,...

Editor: Robert K. Poole Release Date: 22 Apr 2008
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Thiol Redox Transitions in Cell Signaling, Part A...

Editors: Enrique Cadenas & Lester Packer Release Date: 14 Jun 2010
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Nitric Oxide, Part F

Editors: Enrique Cadenas & Lester Packer Release Date: 25 Apr 2008
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Amyloid, Prions, and Other Protein Aggregates, Pa...

Editors: Ronald Wetzel & Indu Kheterpal Release Date: 06 Oct 2006
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Complex enzymes in microbial natural product bios...

Editor: David Hopwood Release Date: 24 Apr 2009
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Small GTPases in Disease, Part A

Editors: W. Balch & Channing Der & Alan Hall Release Date: 25 Apr 2008
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Translation Initiation: Cell Biology, High-throug...

Editor: Jon Lorsch Release Date: 12 Oct 2007
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Fluorescence Spectroscopy

Editors: Ludwig Brand & Michael Johnson Release Date: 11 Dec 2008
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Lipidomics and Bioactive Lipids: Mass Spectromet...

Editor: H. Alex Brown Release Date: 26 Nov 2007
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Stem Cell Tools and Other Experimental Protocols

Editors: Robert Lanza & Irina Klimanskaya Release Date: 12 Dec 2006
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Single Molecule Tools, Part A: Fluorescence Based...

Editor: Nils Walter Release Date: 14 Jun 2010
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RNA Modification

Editor: Jonatha Gott Release Date: 01 Aug 2007
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Computer Methods Part A

Editors: Michael Johnson & Ludwig Brand Release Date: 30 Jan 2009
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Measuring Biological Responses with Automated Mic...

Editor In Chief: James Inglese Release Date: 18 Oct 2006
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Thiol Redox Transitions in Cell Signaling, Part B

Editors: Enrique Cadenas & Lester Packer Release Date: 08 Jul 2010
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Translation Initiation: Extract Systems and Mole...

Editor: Jon Lorsch Release Date: 15 Oct 2007
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Globins and Other Nitric Oxide-Reactive Proteins,...

Editor: Robert K. Poole Release Date: 05 Feb 2008
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Chemokines, Part A

Editors: Tracy Handel & Damon Hamel Release Date: 27 May 2009
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Osmosensing and Osmosignaling

Editors: Helmut Sies & Dieter Haeussinger Release Date: 01 Oct 2007
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Adult Stem Cells

Editors: Irina Klimanskaya & Robert Lanza Release Date: 22 Nov 2006
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Lipidomics and Bioactive Lipids: Specialized Ana...

Editor: H. Alex Brown Release Date: 09 Nov 2007
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Oxygen Biology and Hypoxia

Editors: Helmut Sies & Bernard Bruene Release Date: 08 Nov 2007
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Liposomes, Part F

Editor: Nejat Duzgunes Release Date: 19 Nov 2009
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Liposomes, Part G

Editor: Nejat Duzgunes Release Date: 19 Nov 2009
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Mitochondrial Function, Part B, Mitochondrial Pro...

Editors: William Allison & Anne Murphy Release Date: 15 May 2009
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Integrins

Editor: David Cheresh Release Date: 27 Aug 2007
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Autophagy: Lower Eukaryotes and Non-Mammalian Sy...

Editor: Daniel Klionsky Release Date: 12 Dec 2008
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Glycomics

Editor: Minoru Fukuda Release Date: 15 Sep 2010
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Functional Glycomics

Editor: Minoru Fukuda Release Date: 21 Nov 2006
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Nitric Oxide, Part G

Editors: Enrique Cadenas & Lester Packer Release Date: 26 Jun 2008
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Two-Component Signaling Systems, Part A

Editors: Melvin Simon & Brian Crane & Alexandrine Crane Release Date: 03 Jul 2007
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Mitochondrial Function, Part A, Mitochondrial Ele...

Editors: William Allison & Immo Scheffler Release Date: 20 Apr 2009
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Biophysical, Chemical, and Functional Probes of R...

Editor: Daniel Herschlag Release Date: 24 Nov 2009
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Glycomics

Editor: Minoru Fukuda Release Date: 26 Oct 2006
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Single Molecule Tools, Part B: Super-Resolution, ...

Editor: Nils Walter Release Date: 02 Aug 2010
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Two-Component Signaling Systems, Part B

Editors: Melvin Simon & Brian Crane & Alexandrine Crane Release Date: 03 Jul 2007
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RNA Turnover in Bacteria, Archaea and Organelles

Editors: Lynne E. Maquat & Cecilia Arraiano Release Date: 19 Dec 2008
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Glycobiology

Editor: Minoru Fukuda Release Date: 15 Sep 2010
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Two-Component Signaling Systems, Part C

Editors: Melvin Simon & Brian Crane & Alexandrine Crane Release Date: 11 Mar 2010
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Autophagy in Mammalian Systems, Part B

Editor: Daniel Klionsky Release Date: 27 Jan 2009
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Functional Glycomics

Editor: Minoru Fukuda Release Date: 15 Sep 2010
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Computer Methods Part B

Editors: Michael Johnson & Ludwig Brand Release Date: 19 Nov 2009
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Non-Natural Amino Acids

Editors: Tom W. Muir & John Abelson Release Date: 14 Aug 2009
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Biothermodynamics Part A

Editors: Michael Johnson & Jo Holt & Gary Ackers Release Date: 24 Mar 2009
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Hormone Action, Part A, Steroid Hormones, Volume ...

Editors: Bert O'Malley & Joel Hardman Release Date: 28 Jan 1975
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Interferons, Part B, Volume 79: Inteferons Part B

Editor: Sidney Pestka Release Date: 28 Dec 1981
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Prostaglandins and Arachidonate Metabolites, Volu...

Editors: William Lands & William Smith Release Date: 28 Aug 1982
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Proteolytic Enzymes, Part B, Volume 45: Prpteolyt...

Editor: Laszlo Lorand Release Date: 28 Dec 1976
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Enzyme Structure, Part G, Volume 49: Enzyme Struc...

Editors: C. Hirs & Serge Timasheff Release Date: 28 Mar 1978
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Enzyme Structure, Part E, Volume 47: Enzyme Struc...

Editors: C. Hirs & Serge Timasheff Release Date: 28 Nov 1977
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Carbohydrate Metabolism, Part C, Volume 42: Carbo...

Editor: Willis Wood Release Date: 28 Apr 1975
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Carbohydrate Metabolism, Part B, Volume 41: Carbo...

Editor: Willis Wood Release Date: 28 Apr 1975
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Complex Carbohydrates, Part D, Volume 83: Complex...

Editor: Victor Ginsburg Release Date: 28 Apr 1982
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Enzyme Kinetics and Mechanism, Part A: Initial Ra...

Editor: Daniel Purich Release Date: 28 Nov 1979
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Enzyme Kinetics and Mechanism, Part B: Isotopic P...

Editor: Daniel Purich Release Date: 28 Mar 1980
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Enzyme Structure, Part H, Volume 61: Enzyme Struc...

Editors: C. Hirs & Serge Timasheff Release Date: 28 Aug 1979
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Carbohydrate Metabolism, Part D, Volume 89: Carbo...

Editor: Willis Wood Release Date: 28 Sep 1982
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Complex Carbohydrates, Part C, Volume 50: Complex...

Editor: Victor Ginsburg Release Date: 28 Jun 1978
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Photosynthesis and Nitrogen Fixation, Part B, Vol...

Editor: Anthony San Pietro Release Date: 28 Sep 1972
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Enzyme Structure, Part F, Volume 48: Enzyme Struc...

Editors: C. Hirs & Serge Timasheff Release Date: 28 Mar 1978
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Microbial Growth in Biofilms, Part A: Development...

Editor: Ron Doyle Release Date: 25 May 2001
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Ribonucleases, Part B: Artificial and Engineered ...

Editor: Allen Nicholson Release Date: 21 Sep 2001
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Energetics of Biological Macromolecules, Part E

Editors: Jo Holt & Michael Johnson & Gary Ackers Release Date: 05 Mar 2004
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Protein Phosphatases

Authors: Susanne Klumpp & Josef Krieglstein Release Date: 12 Dec 2003
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G Protein Pathways, Part B: G Proteins and Their ...

Editors: Ravi Iyengar & John Hildebrandt Release Date: 11 Dec 2001
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Hyperthermophilic Enzymes, Part B

Editors: Michael Adams & Roger Kelly Release Date: 07 Mar 2001
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Gene Therapy Methods

Editor: M. Ian Phillips Release Date: 22 Feb 2002
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Antisense Technology, Part A, General Methods, Me...

Editor: M. Ian Phillips Release Date: 25 Oct 1999
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Cytochrome P450, Part C, Methods in Enzymology

Editors: Eric Johnson & Michael Waterman Release Date: 25 Oct 2002
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Phase II Conjugation Enzymes and Transport Systems

Editors: Helmut Sies & Lester Packer Release Date: 28 Nov 2005
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DNA Repair, Part A

Editors: Judith Campbell & Paul Modrich Release Date: 28 Apr 2006
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GTPases Regulating Membrane Targeting and Fusion

Editors: W. Balch & Channing Der & Alan Hall Release Date: 13 Dec 2005
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Guide to Yeast Genetics and Molecular and Cell Bi...

Editor: UNKNOWN AUTHOR Release Date: 18 Jun 2002
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Numerical Computer Methods, Part C

Editors: Michael Johnson & Ludwig Brand Release Date: 29 Jun 2000
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