Essential Neuromodulation

Essential Neuromodulation, 1st Edition

Essential Neuromodulation, 1st Edition,Jeffrey Arle,Jay Shils,ISBN9780123814098

Arle   &   Shils   

Academic Press




229 X 152

The only concise, practical reference to address the clinical implications of neuromodulation therapy, its mechanisms, devices, and their management.

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Key Features

  • Chapters offer point-counterpoint commentary for varied perspectives
  • Appendix distills current guidelines in easy, accessible format
  • Chapters follow story of patient care, effectively emphasizing general principles with supporting examples
  • Offers outstanding scholarship, with over 20% of chapters involving international contributors


Neuromodulation is an emerging field that explores the use of electrical, chemical, and mechanical interventions to heal neurological deficits. Such neurostimulation has already shown great promise with disorders and diseases such as chronic pain, epilepsy, and Parkinson’s disease. This is the first concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuro-residents, fellows, and basic clinical practitioners, edited by two prominent clinical experts in the field.

This volume emphasizes essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications, and complication avoidance. There are commonalities to all neuromodulation procedures that must be brought to the forefront to form a cohesive presentation of neuromodulation, and such emphasis will give readers a more solid grounding in the fundamentals needed to embrace this field as a cohesive clinical entity.


Academic clinicians in neurophysiology, neurological diseases, behavioral neuroscience, sensory neuroscience, neuroanatomy and neurosurgery; biomedical engineers looking to understand the clinical aspects of neuro-therapies

Jeffrey Arle

Affiliations and Expertise

Associate Professor of Neurosurgery, Harvard Medical School, Boston, MA, USA

Jay Shils

Affiliations and Expertise

Rush University Medical Center, Director of Intraoperative Neurophysiological Monitoring; Associate Professor, Rush University Medical Center in the Department of Anesthesiology, Chicago, IL, USA

Essential Neuromodulation, 1st Edition



Chapter 1. The Neuromodulation Approach

Chapter 2. Cerebral – Surface

Chapter 3. Cerebral – Deep

Chapter 4. Spinal – Extradural

Chapter 5. Peripheral Nerve

Chapter 6. The Electrode – Materials and Configurations

Chapter 7. The Electrode – Principles of the Neural Interface

Chapter 8. The Electrode – Principles of the Neural Interface

Chapter 9. Device Materials, Handling, and Upgradability

Chapter 10. Electronics

Chapter 11. Power

Chapter 12. Surgical Techniques

Chapter 13. Trials and Their Applicability

Chapter 14. Limiting Morbidity

Chapter 15. Intraoperative Evaluation

Chapter 16. Programming – DBS Programming

Chapter 17. Programming – SCS

Chapter 18. Safety Concerns and Limitations

Chapter 19. Expectations and Outcomes

Chapter 20. Neuromodution Perspectives



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