Alexander R Lyon


Alexander R Lyon

Alexander R. Lyon MA, BM, BCh, MRCP PhD Walport Clinical Lecturer and Specialist Registrar in Cardiology, Imperial College and Imperial College Healthcare NHS Trust, London, UK Alexander Lyon is a Cardiology Specialist Registrar and Walport Clinical Lecturer in Cardiology at Imperial College London. Dr Lyon studied Medicine at Oxford University where he took a 1st Class degree in Physiological Sciences in 1995, achieving second place in the final honours school. After qualifying from the John Radcliffe Medical School in 1998, he trained as a junior doctor in Cardiology in Oxford, the Royal Brompton Hospital and Sydney, Australia. He joined the Cardiac Medicine research group of Professor Sian Harding and Professor Philip Poole-Wilson, where he studied the influence of cardiac gene therapy upon ventricular arrhythmia generation. He was awarded a MRC Clinical Research Training Fellowship in 2005. He completed his PhD in 2008, and spent his first postdoctoral year studying the spatiotemporal patterns of mitochondrial function in the lab of Fadi Akar and Roger Hajjar at Mount Sinai School of Medicine, New York. He was appointed Walport Clinical Lecturer in Cardiology in October 2008. His main research interests include: 1. Abnormal calcium physiology in heart failure. 2. Mechansims of ventricular arrhythmias in heart failure. 3. Biological therapies for heart failure - these include gene therapy, stem cell therapy and myocardial tissue engineering. 4. Spatio-temporal patterns of mitochondrial dysfunction in the intact heart. 5. Influence of stress and high catecholamine levels on cardiac function. Recent academic awards include the Royal Society of Medicine Cardiology Section President’s Medal Winner (2007), Medical Research Society Raftery Prize in Cardiovascular Sciences winner (2008), European Meeting of International Society of Heart Research Best Scientific Poster Prize (2008). He has presented at numerous national and international meetings in the field of cardiac calcium pathophysiology and gene therapy in heart failure. He is currently supervisor for two Imperial College PhD students.

Affiliations and Expertise